Aerobic Ruthenium-Catalyzed C–H Activations
by Alexander Bechtoldt
Date of Examination:2018-08-17
Date of issue:2018-08-31
Advisor:Prof. Dr. Lutz Ackermann
Referee:Prof. Dr. Lutz Ackermann
Referee:Prof. Dr. Konrad Koszinowski
Referee:Prof. Dr. Manuel Alcarazo
Referee:Prof. Dr. Dietmar Stalke
Referee:Dr. Franziska Thomas
Referee:Dr. Max Hansmann
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Description:Dissertation
Abstract
English
Within the last decades C–H activation processes have evolved from a promising concept to a powerful class of reactions for the construction of organic molecules, especially pharmaceutically active compounds. Within this thesis, new and improved synthetic transformations based on C–H activation by ruthenium(II) catalysis, in combination with the use of renewable chemicals, were developed. Additionally, a catalyst system for the effective hydrogen isotope exchange (HIE) on alkenes was explored.
Keywords: C–H Activation; Ruthenium(II) catalysis; Green solvents; Green Chemistry; Alkenylation; Hydrogen Isotope Exchange (HIE)