Modulating verbal episodic memory encoding with transcranial electrical stimulation

by Gabriel Amador de Lara
Doctoral thesis
Date of Examination:2018-10-22
Date of issue:2018-10-29
Advisor:Prof. Dr. Walter Paulus
Referee:Prof. Dr. Walter Paulus
Referee:Prof. Dr. Lars Penke
Persistent Address: http://dx.doi.org/10.53846/goediss-7118

 

 

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Abstract

English

Non-invasive brain stimulation (NIBS) are techniques widely employed in the last decades to the study of physiology of cognitive processes, and bring the promise of being a complementary therapeutic intervention to neuropsychiatric disorders. In this doctoral dissertation, I attempted to advance in methodologically rigorous protocols to influence normal brain physiology and search for solutions to modulate memory activity, targeting different anatomical nodes of the verbal episodic memory network with transcranial electrical stimulation (tDCS, TACS). In the first study, I aimed to modulate memory performance by applying a focal multi-electrode tDCS targeting primarily the dorso-lateral pre-frontal cortex (DLPFC). In the second study, the target was moved to the left temporal cortex, aiming to interfere and manipulate with the temporal characteristics of the encoding process by the application of tACS.
Keywords: episodic memory; tDCS; tACS; long-term memory; brain stimulation
 
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