Browsing GGNB - Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und molekulare Biowissenschaften by Referee "Wörgötter, Florentin Prof. Dr."
Now showing items 1-20 of 24
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Proactive planning of action sequences
(2024-07-05)Everyday tasks often require a sequence of actions. Knowing which actions will follow, allows us to proactively prepare for subsequent actions before the first action has been executed. This thesis investigated the neural ... -
Neural network integration from multimodal imaging in epilepsy and healthy controls
(2024-01-17)Different imaging modalities can be used to probe distinct aspects of the brain, such as cerebral anatomy (MRI), tissue diffusion directions (DTI), metabolic activity (PET), neurovascular activity (fMRI), or electrophysiological ... -
Reconstructing the electrical dynamics on the heart
(2022-11-09)The heart is an electro-mechanical system. In 2010 about 4.25 million people died from cardiac arrhythmias. Immediate treatment in case of fibrillation is to shock the heart electrically with high energy to reset the ... -
Simulation of fronto-parietal neural population activity to probe dimensionality reduction methods.
(2022-09-20)Recent developments of optical and electrophysiological recording tools allow the detailed capture of large neuronal populations. Findings show that their activity is constrained to a low-dimensional manifold within the ... -
Manipulating neuronal communication by using low-intensity repetitive transcranial magnetic stimulation combined with electroencephalogram
(2021-11-18)Repetitive transcranial magnetic stimulation (rTMS) modulates ongoing brain rhythms by activating neuronal structures and evolving different neuronal mechanisms. In the current work, the role of stimulation strength and ... -
Drift and stabilization of cortical response selectivity
(2021-08-02)Synaptic turnover and long term functional stability are two seemingly contradicting features of neuronal networks, which show varying expressions across different brain regions. Recent studies have shown, how both of these ... -
Molecular and structural correlates of ocular dominance plasticity in mice
(2020-11-11)During early postnatal life, the brain goes through critical periods of increased plasticity, which enable experience-dependent refinements of neuronal circuits. Insertion of α-amino- 3-hydroxy-5-methyl-4-isoxazolepropionic ... -
The role of attention and adaptation in shaping cortical representations and the perception of abrupt changes in the visual environment
(2017-11-22)The visual system receives a wealth of visual information about objects with changing features in time. Attention is a mechanism allowing us to prioritize the processing of relevant information at the expense of other ... -
On the Speed of Neuronal Populations
(2017-10-10)This thesis presents novel results in the areas of closed loop electrophysiology and neuronal population coding. This work begins by presenting the first known attempt to control the spike rate of a neuron or neurons using ... -
Peripheral nervous system control for neuroprostheses
(2017-09-21)Amputee patients who have lost a hand or arm are severely impaired in their daily life, as they lose the ability to grasp and interact with their environment. While the use of electromyographically controlled prosthetic ... -
Food Distribution in Ant Colonies: Trophallaxis and Self-Organization
(2017-09-14)Roughly one hundred million years ago, solitary insect species evolved social interactions that enabled the formation of colonies. A main reason for this advance was their ability to feed each other with previously ... -
Electrocutaneous stimulation to close the loop in myoelectric prosthesis control
(2017-08-09)Current commercially available prosthetic systems still lack sensory feedback and amputees are forced to maintain eye-contact with the prosthesis when interacting with their environment. Electrocutaneous stimulation is a ... -
Investigation of voltage- and light-sensitive ion channels
(2016-08-09)In this work, the properties of ion channels in biological membranes are characterized. Two systems are investigated: The conductance changes of the membrane of the axon initial segment (AIS) due to fast sodium channels, ... -
The Effect of Finite Temperature on the Jamming Transition
(2016-05-30)We study the effect of finite temperatures on spring networks obtained from amorphous, jammed packings of repulsive spheres. By means of a Monte Carlo Metropolis scheme, we analyse this two-dimensional model of an amorphous ... -
Reference frames for planning reach movement in the parietal and premotor cortices
(2016-02-16)Human and nonhuman primates are able to plan and execute goal-directed behavior and flexibly respond to their surrounding stimuli. Their ability to adapt to changes in their environment is a crucial factor for their ... -
Modular Architecture for an Adaptive, Personalisable Knee-Ankle-Foot-Orthosis Controlled by Artificial Neural Networks
(2015-12-11)Walking is so fundamental in everyday life that it is, for most people, an unconscious action. Loss or limitations in the ability to walk or stand directly impair our mobility and independence. Reasons of limitations can ... -
Temporal information processing and memory guided behaviors with recurrent neural networks
(2015-02-25)The ability to quantify temporal information on the scale of hundreds of milliseconds is critical towards the processing of complex sensory and motor patterns. However, the nature of neural mechanisms for temporal information ... -
Myoelectric Signal Processing for Prosthesis Control
(2015-02-03)The myoelectric signal (MES) is the electrical manifestation of contraction. The MES, recorded at the surface of the skin, has been exploited as a control source for powered upper limb prosthetics. The primary objective ... -
Development of new computational methods for non-invasive brain stimulation
(2014-07-21)In this thesis, we explore the use of computational models that numerically solve the electric field during TMS and tDCS in order to improve the spatial precision of these methods. For TMS, we validate the prediction of ... -
Reading memory traces in cultured neuronal networks by probabilistic analysis
(2014-02-21)In this thesis, I am studying the enhancement of the collective burst dynamics, burst activation and propagation in hippocampal neuronal networks in-vitro by using optogenetic techniques. Channelrhodopsin-2 transfected ...