Browsing GGNB - Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und molekulare Biowissenschaften by Advisor "Rodnina, Marina Prof. Dr."
Now showing items 21-25 of 25
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Mechanisms of programmed ribosomal -1 frameshifting in bacteria
(2014-07-15)Translation of proteins must be accurate to synthesize functional proteins. However, in some cases gene information is reprogrammed which overwrites the normal decoding rules of translation. One of these cases is programmed ... -
Kinetic Dissection of Translation Initiation in Prokaryotes.
(2014-01-08)Ribosomes are nucleoprotein complexes which synthesize proteins in the cells. The process of translation can be subdivided into several phases: translation initiation, elongation, termination and ribosome recycling. The ... -
Coupling of GTP hydrolysis by EF-G to tRNA and mRNA translocation through the ribosome
(2013-09-20)Translocation is the concerted movement of the messenger RNA (mRNA) and the transfer RNA (tRNA) through the ribosome. Although spontaneous in vitro, this process is catalyzed by the translational GTPase elongation factor ... -
Molecular mechanisms of substrate selection and protein folding on the ribosome
(2013-06-18)Aminoacyl-tRNA (aa-tRNA) is delivered to the ribosome in a ternary complex with elongation factor Tu (EF-Tu) and GTP. Cognate codon-anticodon interaction induces rapid GTP hydrolysis and allows aa-tRNA to accommodate on ... -
Molecular mechanism of selenocysteine incorporation in bacterial translation
(2012-06-27)Selenocysteine is the 21st amino acid which is incorporated into proteins by recoding a stop codon UGA followed by a selenocysteine insertion sequence (SECIS) of the mRNA. In bacteria, selenocysteine insertion requires ...