Browsing GGNB - Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und molekulare Biowissenschaften by Referee "Janshoff, Andreas Prof. Dr."
Now showing items 21-32 of 32
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Membrane tension homeostasis of mammalian cells
(2017-04-12)Although a cell is the smallest unit that is viable on its own, its construction and processes are of great complexity. Many functions, which keep a cell alive, are only poorly understood up to now. Plasma membrane tension ... -
Biogenesis and maintenance of cytoplasmic domains in myelin of the central nervous system
(2017-02-27)Myelin is a multi-lamellar membrane structure, produced by oligodendrocytes which are special glial cells, that myelinate axons in the central nervous system (CNS) (Aggarwal, Yurlova, & Simons, 2011; Vassall, Bamm, & Harauz, ... -
Cellular locomotion and adhesion in the context of different substrate properties
(2017-01-16)This work comprises three different projects dealing with the interplay of cellular locomotion and adhesion to establish a better understanding of the response of cells to their environment. In the first part of this thesis ... -
Forces in Cellular Growth and Division
(2016-02-05)Under confinement cell populations exert growth forces onto their surroundings. Confined cell populations can be found plentiful in nature, e.g. tumors embedded in healthy tissues, microbial populations in stone cavities ... -
Oscillatory instabilities of intracellular fiber networks
(2015-12-02)D. discoideum shares many common features of actin dynamics and essential responses with eukaryotic cells and cancer cells. Therefore, most properties of the oscillations are well studied in the simpler biological model ... -
Nanoscale organization and dynamics of SNARE proteins in the presynaptic membranes
(2015-10-19)The specific organization of proteins and lipids in functional domains in biological membranes allows localization and segregation of specific physiological activities. Mechanisms that underlie the formation of these domains ... -
Actin turnover regulates mechanical properties of oligodendrocytes and myelin formation
(2015-10-02)The myelin sheath is a specialized membranous structure that facilitates rapid signal conduction along axonal segments. During central nervous system development, it is formed by oligodendrocytes that extend motile and ... -
Dynamics and mechanics of adherent cells in the context of environmental cues
(2015-03-25)Cellular behavior is influenced by many biochemical but also physical factors in the direct cellular environment. Thereby, cells not only react to external cues, the interaction between cells and their environment is also ... -
Combining force and fluorescence microscopy for the manipulation and detection of single cells, viruses, and proteins
(2014-10-13)Total Internal Reflection Fluorescence Microscopy (TIRFM) and Atomic Force Microscopy (AFM) are both successfully applied in biophysics and biology. AFM provides the possibility to image and to mechanically manipulate the ... -
Keratin Networks in Live Cells
(2014-09-26)Intermediate filaments are a major component of the eukaryotic cytoskeleton along with microtubules and microfilaments and play a key role in cell mechanics. One representative of this class of proteins, which exemplifies ... -
Role of cellular dynamics, adhesion and polarity in the context of primordial germ cell migration in Xenopus laevis embryos
(2014-02-11)Directional cell migration is an intensively studied process relevant for both normal development of an organism as well as for a number of pathological conditions such as chronic inflammation and cancer. Primordial germ ... -
Spatial-temporal actin dynamics during synaptic plasticity of single dendritic spine investigated by two- photon fluorescence correlation spectroscopy
(2013-12-19)In the content of my thesis, the construction and calibration of a setup that combined conventional wide field fluorescence microscopy (FM) and two-photon fluorescence correlation spectroscopy (2P-FCS) was first described. ...