Browsing GGNB - Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und molekulare Biowissenschaften by Referee "Wodarz, Andreas Prof. Dr."
Now showing items 21-28 of 28
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The role of <i>Satb2</i>, <i>Ctip2</i> and Fezl in cortical connectivity and the elucidation of their downstream pathways
(2012-06-06)Satb2 has been shown to be a key postmitotic determinant of callosal projection neurons (Alcamo et al., 2008; Britanova et al., 2008). One way by which Satb2 is acting to confer such identity involves the repression of Ctip2, ... -
Molecular mechanism of B cell antigen receptor-induced SHIP activation
(2012-03-05)Regulation of B cell activation is highly important to keep the balance between immunity and self-tolerance. The SH2 domain-containing 5 inositol phosphatase (SHIP) is an inhibitor of B ... -
Identification and characterization of molecular mechanisms driving the functional specification of motor neurons The Delta like homolog 1 protein
(2012-03-02)Spinal Motor neurons are playing a decisive role in body posture and locomotion by controlling skeletal muscle contraction via their motor axon termini. During embryonic development motor ... -
Identification and functional characterization of PTK7 ligands in Xenopus laevis
(2011-10-26)Wnt signaling pathways are evolutionary conserved and regulate numerous processes in both developing and adult organisms. The canonical Wnt signaling pathway regulates cell proliferation ... -
A novel phosphatase modulating the DNA damage response and the tumor suppressor p53
(2011-09-21)The cellular genome is constantly exposed to harmful endogenous and exogenous factors. Unrepaired DNA lesions and mismatches promote genomic instability, a major cause of cancer. Therefore, ... -
Neuroligin 2 Induced Allosteric Transition of Collybistin Underlies Inhibitory Postsynaptic Differentiation
(2011-06-03)Synaptic inhibition is vital to brain function. GABAergic and glycinergic synapses, mediating fast inhibition in the mammalian central nervous system (CNS), balance the activity of neural circuits. At the inhibitory ... -
The role of the novel endosomal protein Rush hour (CG14782) in endosomal trafficking in Drosophila melanogaster
(2011-03-29)Endocytosis regulates multiple cellular processes, including the protein composition of the plasma membrane, intercellular signaling and cell polarity. Cell polarity is defined by asymmetric ... -
The function of PTK7 during Xenopus neural crest migration
(2009-12-18)PTK7 is a novel component of the planar cell polarity (PCP) signaling pathway, which regulates inner ear hair cell polarity and neural tube closure, however, its signaling mechanism is ...