Browsing GGNB - Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und molekulare Biowissenschaften by Referee "Wolf, Fred Prof. Dr."
Now showing items 21-40 of 41
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The role of Calcium Binding Protein 2 in synaptic sound encoding and hearing
(2016-11-29)Hearing is a unique sensory feature providing the individual with acoustic information about the surrounding environment. Humans rely on hearing to localize potential dangers and it is essential for communication and social ... -
Physiological Classification of Retinal Ganglion Cells in the Salamander Retina
(2016-04-13)The retina is a complex neural network, responsible for breaking down the visual scene into its distinctive features such as local contrast, motion and color. The retinal ganglion cells form the output layer of this ... -
Processing of Graded Signaling Systems
(2016-03-24)Vocal repertoires of nonhuman animals and especially of terrestrial mammals are often characterized by their relatively small size of innate vocal types which can show considerable variation in acoustic structure. To ... -
Cellular dynamics and stable chaos in balanced networks
(2016-01-22)A prudent approach to understanding the function of the cerebral cortex begins with understanding the repertoire of its dynamics. In this thesis, I study how interactions between single neuron properties, synaptic coupling, ... -
Attention: A Complex System
(2015-12-21)Experiments have elucidated the neuronal correlates of attention in the primate brain, and have led to a number of models capturing various aspects of these experiments. However, these model propose qualitatively different ... -
Continuous detection and prediction of grasp states and kinematics from primate motor, premotor, and parietal cortex
(2015-05-11)Neuroprosthetics aim to restore a paralyzed patient’s ability to interact with the environment, e.g., by enabling the patient to control a robot arm and hand with his or her brain activity by decoding movement intentions ... -
Sound Encoding in the Mouse Cochlea: Molecular Physiology and Optogenetic Stimulation
(2014-04-24)Afferent synapses between inner hair cells (IHCs) and spiral ganglion neurons in the cochlea translate sound information into a discrete spike code, providing us the opportunity to directly observe the output of the cochlea. ... -
Reading memory traces in cultured neuronal networks by probabilistic analysis
(2014-02-21)In this thesis, I am studying the enhancement of the collective burst dynamics, burst activation and propagation in hippocampal neuronal networks in-vitro by using optogenetic techniques. Channelrhodopsin-2 transfected ... -
Impact of stroke and enriched environment on visual cortical plasticity in mice and therapeutic interventions for rehabilitation
(2014-02-18)Stroke is a major cause of death and disability in industrialized countries. Cortical plasticity is crucial for recovery and rehabilitation after a stroke. The aims of the study were to investigate the impact of a ... -
Synaptic physiology of the cochlear sound encoding
(2013-11-27)Sound intensity is encoded as action potential firing rates by spiral ganglion neurons. These neurons show different rate-level functions with different auditory thresholds, and are thought to collectively encode the large ... -
Numerical Simulations on the Biophysical Foundations of the Neuronal Extracellular Space
(2013-11-25)The electric activity of neurons creates extracellular potential fields. Recent findings show that these endogenous fields act back onto the neurons, contributing to synchronization of population activity. The influence ... -
Neuronal basis of goal-directed reach planning under reversed vision in the parietal and premotor cortices
(2013-10-09)In our everyday life we can produce goal-directed movements precisely and effortlessly, for example to saccade towards a location that you are interested in, or to reach and grasp for a cup of coffee. Goal-directed behaviors ... -
Spatial, feature and temporal attentional mechanisms in visual motion processing
(2013-06-27)The three projects documented in this thesis investigated the role of three forms of attention in visual processing. Spatial, feature-based and temporal attention. The spatial and feature-based attentional characteristics ... -
Optimization principles and constraints shaping visual cortical architecture
(2012-05-03)Neurons in the mammalian primary visual cortex (V1) are often preferentially driven by only one of the two eyes and respond best to oriented bar stimuli at a particular position in the visual field. Most carnivorans and ... -
Theoretical analysis of membrane properties underlying action potential phase-locking in noise-driven cells
(2011-12-09)How does the brain work? This very broad and yet, very crucial and interesting question appealed scientists from various disciplines to itself. The fact that the operation of a system of ... -
Neuronal mechanisms of the adaptation of conditional visuomotor behavior
(2011-10-20)Goal directed movements are guided by sensory inputs, which define the spatial constraints for such movements. Our vision, and also our other senses, give us information about the location ... -
Detection and functional analysis of Ca2+ microdomains and BK channels in olfactory receptor neurons of larval Xenopus laevis
(2011-09-21)Olfactory receptor neurons (ORNs) sense odors through the interaction of odorants with their receptors, accomplishing the first step of olfactory signaling via the generation of action ... -
Theoretical Studies of the Dynamics of Action Potential Initiation and its Role in Neuronal Encoding
(2011-08-08)In this thesis analytically solvable neuron models are constructed to study the influence of the initiation speed and location of AP (action potential) generation on the dynamical response ... -
Chaotic Dynamics in Networks of Spiking Neurons in the Balanced State
(2011-05-30)The brain processes sensory information about the outside world in large complex networks of neurons which communicate with short electrical pulses called action potentials or spikes. The ... -
Topological Optimization in Network Dynamical Systems
(2011-04-05)In this thesis we look at results concerning two separate topics.The first topic belongs to the general problem of reconstruction of interaction networks using only per-site information. ...