Browsing GGNB - Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und molekulare Biowissenschaften by Title
Now showing items 330-349 of 1199
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Fast and Robust Multi-Dimensional Cardiac Magnetic Resonance Imaging
(2020-09-02)Magnetic Resonance Imaging (MRI) has become an almost indispensable tool in hospitals worldwide as it provides significant and unique information for the assessment of various disease and injuries. However, MRI is an ... -
Feature Selectivity in Synthetic Neuronal Networks
(2024-06-06)A fundamental property of neurons in the primary visual cortex is their preference for orientation of edges. In primates and carnivores orientation selective neurons are organized into functional domains that are arranged ... -
Feature-based attention in primate visual cortex
(2016-07-06)The scope of this thesis, after a brief summary of the core ideas of top-down attentional control is given (Chapter 2.1), is to shed some light on the cortical control circuit underlying the deployment of feature-based attention. ... -
Flows, morphology, and memory: study of a living network
(2020-06-22)The complex behaviour of the slime mould Physarum polycephalum, a simple eukaryote, has been puzzling researchers since its discovery. The giant unicellular, but multinucleate organism is highly successful at tackling ... -
Fluctuations and Oscillatory Instabilities of Intracellular Fiber networks
(2015-11-10)Biological systems with their complex biochemical networks are known to be intrinsically noisy. The interplay between noise and dynamical behavior is particularly relevant in the case of chemotactic amoeboid cells as their ... -
Fluorescence Correlates of Single Vesicles to Analyze the Behavior of Membrane-manipulating Proteins
(2025-01-24)Soluble NSF-attachment protein receptors (SNAREs) are integral to eukaryotic membrane fusion, providing the necessary energy to surmount the repulsive forces between two opposing membranes. This is achieved through the ... -
Fluorescence correlation spectroscopy for studying intermediate filament assembly
(2017-08-10)Intermediate filaments play a central role in the cytoskeleton of eukaryotic cells. Together with microtubules and actin filaments they determine the mechanical properties of cells. Microtubules are also the guiding tracks ... -
Fluorescence Lifetime Single Molecule Localisation Microscopy
(2021-03-26)In conventional fluorescence microscopy, species are distinguished by colour. While these images provide an abundance of information about the sample, they are, in many aspects limited by artefacts and resolution, and some ... -
Fluorescence spectroscopic studies of protein conformational dynamics
(2013-10-31)The folding of a protein into its native structure is the fundamental prerequisite for its functionality. The polypeptide chain itself contains the chemical information necessary for spontaneous folding of the protein. ... -
Food Distribution in Ant Colonies: Trophallaxis and Self-Organization
(2017-09-14)Roughly one hundred million years ago, solitary insect species evolved social interactions that enabled the formation of colonies. A main reason for this advance was their ability to feed each other with previously ... -
Force information integration in the primate fronto-parietal reach network
(2023-11-10)The primate sensorimotor system relies on force predictions, when executing a motor command with a certain force. Yet it remains unclear if the sensorimotor system uses these force predictions to prepare a motor command ... -
Forces in Cellular Growth and Division
(2016-02-05)Under confinement cell populations exert growth forces onto their surroundings. Confined cell populations can be found plentiful in nature, e.g. tumors embedded in healthy tissues, microbial populations in stone cavities ... -
Formation, regulation and dynamics of phase separated postsynaptic density condensates with Tau and Fyn
(2024-11-22)Alzheimer’s disease is characterized by memory loss and cognitive impairments. The cognitive deficits and synaptic dysfunction are associated with the excitotoxicity mediated by NMDA (N-methyl-D-aspartate) receptors on the ... -
Foundations of Stochastic Thermodynamics
(2015-03-17)Small systems in a thermodynamic medium --- like colloids in a suspension or the molecular machinery in living cells --- are strongly affected by the thermal fluctuations of their environment. Physicists model such ... -
From a First Seizure to Chronic Epilepsy – A Structural and Functional Study
(2025-01-23)Diagnosing epilepsy after a first unprovoked seizure is challenging, especially in patients without detectable lesions on standard magnetic resonance imaging (MRI) and without interictal epileptiform discharges (IEDs) ... -
From annotation to bacterial data models
(2022-06-24)Science and technological advancements walk side-by-side and with the recent emergence of novel high throughput techniques, the necessity to have specialized data structures to host and represent the complex and high variety ... -
From hearing to singing:sensory to motor information processing in the grasshopper brain
(2016-08-02)Grasshoppers, and among them especially the species Chorthippus biguttulus, have been used as a model system to study the neuronal basis of acoustic behavior. Auditory neurons have been described from intracellular recordings. ... -
From inside-out to outside-in: cortical lamination development in the Reelin-deficient neocortex
(2019-03-15)The adult mammalian neocortex is divided into six vertical layers, as well as into numerous specialized tangential areas that are defined by distinct cytoarchitectures and specific wiring patterns. Precise neocortical ... -
From Paramagnetic Proteins to Field Alignment of Small Molecules
(2022-03-17)In this dissertation we show how to push the boundaries of structure elucidation using tensorial NMR parameters. Possible sources for these effects are paramagnetic centers or molecular alignment, and they contain valuable ... -
From screening to function - Evolutionary conservation of novel JAK/STAT signal transduction pathway components
(2007-04-03)Signal transduction pathways mediating the exchange of information between cells are essential for development, cellular differentiation and homeostasis. Their dysregulation is also frequently ...