Browsing GGNB - Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und molekulare Biowissenschaften by Advisor "Bastians, Holger Prof. Dr."
Now showing items 1-4 of 4
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A Mitotic Actin Regulating Pathway Induces Chromosomal Instability In Human Cancer Cells
(2020-06-11)Chromosome instability (CIN) is a hallmark of human cancer and causes structural (S-CIN) as well as whole (W-CIN) chromosome aberrations. Cancers exhibiting the CIN phenotype are characterized by a large genetic heterogeneity ... -
A Role For Microtubule Dynamics For The Induction Of Chromosomal Instability And Cell Migration And Invasion In Human Cancer Cells
(2017-06-21)Aneuploidy and increased cell migration and invasion are hallmarks of aggressive human cancers. Aneuploidy derives from an increased rate of perpetual chromosome missegregation during mitosis, referred to as chromosomal ... -
Investigation of the role of microtubule dynamics in paracrine signaling and cell invasion in human cancer cells
(2021-09-23)Metastasis is a critical characteristic of aggressive human cancer, which is determined by the acquirement of increased cancer cell migration and invasion capabilities. Recent published work indicated that supernumerary ... -
Regulation Of Spindle Orientation By A Mitotic Actin Pathway In Chromosomally Unstable Cancer Cells
(2020-11-18)Aneuploidy is a hallmark of human cancer and is observed in 90 % of solid tumors. The perpetual gain or loss of whole chromosomes, defined as chromosomal instability (CIN), represent one mechanism causing aneuploidy. CIN ...