Blättern GGNB - Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und molekulare Biowissenschaften nach "Braus, Gerhard H. Prof. Dr." Betreuer
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Aspergillus fumigatus F-box protein Fbx15 functions are dependent on its nuclear localisation signals and are partially conserved between A. fumigatus and A. nidulans
(2020-09-08)Aspergillus fumigatus is a globally distributed opportunistic filamentous fungal pathogen mainly found in compost and represents the main cause of pulmonary aspergillosis in immunocompromised individuals. Fungal development ... -
Insertion of an intrinsically disordered domain in VelB supports selective heterodimer formation of fungal velvet domain regulatory proteins in Aspergillus nidulans
(2019-04-10)The fungal specific velvet domain mediates DNA-binding and protein-protein interaction and is structurally similar to the Rel homology domain of the mammalian immune and infection response NF-ᴋB regulator. Homo- and ... -
Interplay of the COP9 signalosome deneddylase and the UspA deubiquitinase to coordinate fungal development and secondary metabolism
(2019-05-29)Protein half-life is controlled through the ubiquitin-proteasome system (UPS). Proteins are labeled with ubiquitin chains by E3 cullin RING ligases (CRLs) and then degraded by the 26S proteasome. The COP9 signalosome (CSN) ... -
The Verticillium dahliae Vta3 genetic network and hydrophobins are required in tomato xylem sap for plant disease
(2023-03-27)The ascomycete Verticillium dahliae is a pathogenic fungus for a variety of important crops and spends long phases of its life cycle in the vascular xylem system of particular host plants. Growth in this unique and ... -
The Zinc cluster transcription factor ZtfA is an activator of asexual development and secondary metabolism and regulates the oxidative stress response in the filamentous fungus Aspergillus nidulans
(2018-06-11)The interconnection of developmental programs and secondary metabolism is regulated by the velvet domain proteins in numerous filamentous fungi. Velvet domain proteins constitute a family of fungal specific transcription ...