Blättern GGNB - Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und molekulare Biowissenschaften nach "Eichele, Gregor Prof. Dr." Betreuer
Anzeige 1-6 von 6
-
Acetyltransferase TIP60/KAT5 regulates the Drosophila Circadian Clock
(2016-10-14)Endogenous clocks control behavioral and physiological processes in a rhythmic fashion exhibiting periodicity of ~24 h. Drosophila exhibits a robust rhythm in activity/rest patterns which is controlled by circadian pacemaker ... -
Molecular characterization and functional analysis of a novel long noncoding RNA in the mouse
(2019-05-24)Majority of mammalian transcriptomes encode long noncoding RNAs (lncRNAs) that are not translated into proteins. LncRNAs are mRNA-like transcripts that are longer than 200 nucleotides, transcribed by RNA-Pol-II and undergo ... -
New genetic mouse models for neurodegenerative diseases: Contribution of noradrenaline to Alzheimer’s disease pathogenesis and creation of a new genetic model for Parkinson’s disease.
(2011-12-15)Neurodegenerative diseases are among the most devastating diseases for which there are no cure to date. The greatest risk factor is advancing age. A common feature of these disorders is the toxic aggregation of a peptide ... -
Spatio-temporal Approach to Transport Dynamics in the Mammalian Ventricular System
(2015-02-19)This thesis addresses circadian regulation of solute transport systems in the brain ventricular system. It was found that transport of solutes between blood and the ventricular lumen are subjected to circadian regulation ... -
Spatio-temporal dynamics in the anchoring of cilia
(2019-10-02)The ventricular system of the mammalian brain consists of the two lateral, a third, and a fourth ventricle that interconnect and are filled with circulating cerebrospinal fluid (CSF) (1). CSF streams along the ventricular ... -
The Role of Lysine Acetyltransferase Tip60 in the Murine Hippocampus
(2015-07-07)Making new memories is a highly complex process, which involves rapid modifications of existing proteins, induction of gene expression, de novo protein synthesis, and the altering of neuronal structures. The cellular ...