Blättern GGNB - Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und molekulare Biowissenschaften nach "Köster, Sarah Prof. Dr." Betreuer

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    • Blood Platelet Behavior on Structured Substrates 

      Sandmann, Rabea (2015-11-02)
      Blood clotting is the immediate answer of the body to injuries. In this process, blood platelets adhere to the injured site, spread over the wound and form a blood clot, in which single platelets are connected by fibrin ...

    • Fluorescence correlation spectroscopy for studying intermediate filament assembly 

      Schroeder, Viktor (2017-08-10)
      Intermediate filaments play a central role in the cytoskeleton of eukaryotic cells. Together with microtubules and actin filaments they determine the mechanical properties of cells. Microtubules are also the guiding tracks ...

    • Influence of Ions on the Assembly of Vimentin Intermediate Filaments 

      Denz, Manuela (2020-07-10)
      The human body consists of many different cell types, which all exhibit a cytoskeleton. This cytoskeleton is mainly composed of three different types of protein filaments, as well as cross-linkers and motor proteins. The ...

    • Intermediate filament mechanics across scales 

      Schepers, Anna V. (2022-02-24)
      The mechanical properties of cells are largely determined by the cytoskeleton. The cytoskeleton is an intricate and complex structure formed by protein filaments, motor proteins, and crosslinkers. The three main types of ...

    • Keratin Networks in Live Cells 

      Nolting, Jens-Friedrich (2014-09-26)
      Intermediate filaments are a major component of the eukaryotic cytoskeleton along with microtubules and microfilaments and play a key role in cell mechanics. One representative of this class of proteins, which exemplifies ...

    • Stress-Strain Behavior of Single Vimentin Intermediate Filaments 

      Block, Johanna Lena (2018-08-09)
      Cells are the basic unit of living organisms and consist of a cytoplasm, which is enclosed by a membrane. As building blocks of life with a plethora of functions, cells have to be equipped with a high degree of mechanical ...

    • The Influence of Substrate Elasticity and Shear Rate on Human Blood Platelet Contraction 

      Hanke, Jana (2018-09-12)
      Human blood platelets are small, anucleate cell fragments that are important for the life-saving process of haemostasis, i.e. the process of wound healing. Upon injury, blood platelets adhere to the exposed extra-cellular ...

    • Tracking Assembly Kinetics of Intermediate Filaments 

      Saldanha, Oliva (2017-04-13)
      Vimentin is an intermediate filament (IF) protein in eukaryotic cells and together with other IFs, actin filament and microtubules plays an instrumental role in providing stability and mechanical properties to the cell. ...

    • Vimentin Intermediate Filament Softening - Recovery Behavior and Post-Translational Modifications 

      Kraxner, Julia (2021-09-16)
      The capability of eukaryotic cells to resist large deformations, to transport intracellular cargo and to adapt the cell shape, for example during migration, depends on the cytoskeleton, a composite network of three types ...