Browsing GGNB - Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und molekulare Biowissenschaften by Advisor "Kessel, Michael Prof. Dr."
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Mad2l2 as a safeguard for open chromatin in embryonic stem cells
(2016-08-08)Open chromatin is induced locally during the repair of DNA double-strand breaks when a cascade of protein recruitments and modifications is triggered. This "ATM cascade" includes components like the Mrn complex, ATM kinase, ... -
Mad2l2 in primordial germ cell development and pluripotency
(2013-11-18)The development of primordial germ cells (PGCs) involves several waves of epigenetic reprogramming. A major step is the transition from the stably suppressive histone modification H3K9me2 to the more flexible, still ... -
Regulation of the homeoprotein Hesx1 via Mad2l2 and the anaphase promoting complex
(2008-09-17)Understanding the functional significance of the coordinate expression and interaction of homeobox transcription factors remains a critical question in developmental biology. Hesx1 is a ...