Browsing GGNB - Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und molekulare Biowissenschaften by Advisor "Walter, Lutz Prof. Dr."
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Analysis of the transcriptome of human NK lymphocytes
(2016-10-31)Natural Killer cells are large granular lymphocytes that contribute to both innate and adaptive immunity, as they can not only lyse infected cells or tumors, but also stimulate an adaptive immune response via production ... -
Characterisation of killer immunoglobulin-like receptors in rhesus macaques (Macaca mulatta)
(2012-10-22)Rhesus macaques are important animal models of human diseases in which NK cells play significant roles. Whereas data on KIR genetic variability were recently published, data on KIR protein expression was not available until ... -
Expression and properties of neuronal MHC class I molecules in the brain of the common marmoset monkey
(2009-11-13)Several recent studies have highlighted the important role of immunity-related molecules in synaptic plasticity processes in the developing and adult rodent brain. It has been suggested that neuronal MHC (major ... -
Genomics of Hybridization and Adaptation in Primates
(2023-12-07)In chapter 1, we used high coverage (30X) whole genome sequences from 225 wild baboons (genus Papio) representing 19 geographic localities to investigate population genomics and inter-species gene flow. Our analyses provide ... -
Phenotypic and Functional Characterization of Natural Killer Cell Receptors in Human and Rhesus macaque
(2024-02-05)Activating killer immunoglobulin-like receptors (KIRs) cannot transmit signals directly but through signaling motifs. Since human activating KIRs lack signaling molecules, their transmembrane lysine residue pairs with ...