Browsing GGNB - Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und molekulare Biowissenschaften by Referee "Dean, Camin Ph.D."
Now showing items 1-6 of 6
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AAV-based gene therapy for axonal regeneration in a rat model of rubrospinal tract lesion
(2015-04-29)Spinal cord injury (SCI) is a devastating and largely irreversible clinical condition, which can lead to permanent sensory and motor functional disabilities. Worldwide, an estimated 2.5 million people suffer from SCI and ... -
Expression and function of Rab3 interacting molecules and clarin-1 in inner hair cells
(2013-09-04)Hearing depends on faithful synaptic transmission at the inner hair cell (IHC) ribbon synapse, which is orchestrated by active zone proteins. RIM (Rab3 Interacting Molecules) is one of the active zone proteins and proposed ... -
Molecular Mechanisms of Astrocyte Vesicle Fusion at Synaptic Interfaces
(2015-12-01)Astrocytes are key to neuronal trophic support, development, and synaptic signalling and plasticity. Astrocytes can detect synaptic events at tripartite synapses –a major site of bidirectional communication between neurones ... -
Nanoscale probing of single synapse function and BDNF Cell-to-Cell transfer
(2016-12-22)Brain-derived neurotrophic factor (BDNF) is one of the key modulator/mediator molecules for synaptic plasticity in the adult nervous system and also coordinates neural development, survival, differentiation and axon growth ... -
The influence of epigenetic alterations on synaptic function and memory
(2022-08-24)While memory formation is traditionally linked to changes in synaptic structure, the transcriptional processes enabling these changes are often understudied. Even though novel protein synthesis is the basis of long-term ... -
Ultrafast Multichannel Optogenetic Stimulation of the Auditory Pathway for Optical Cochlear Implants
(2019-01-14)In case of profound sensorineural hearing loss and deafness, cochlear implants (CIs) partially restore hearing and provide missing auditory information to the brain. Electrical stimulation of the spiral ganglion neurons ...