Dokumente GGNB - Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und molekulare Biowissenschaften nach Gutachter "Eichele, Gregor Prof. Dr."
Anzeige 1-9 von 9
-
Exploring the neural basis of touch through selective and stable genetic tagging in the chick somatosensory system
(2013-01-03)The assembly of circuitries for somatosensory perception relies on a complex interplay of neuronal diversification, specification, phenotypic modulation and establishment of precise connectivity patterns during embryogenesis. ... -
Investigating the Re-initiation of Segmentation with Temporally Restricted RNAi in Tribolium castaneum
(2020-10-01)Much of the success of arthropods is attributed to their body’s segmentation. Segmentation provides various opportunities for nature to evolve new structures without greatly impacting overall fitness of the animal. Most ... -
Mad2l2 in primordial germ cell development and pluripotency
(2013-11-18)The development of primordial germ cells (PGCs) involves several waves of epigenetic reprogramming. A major step is the transition from the stably suppressive histone modification H3K9me2 to the more flexible, still ... -
MicroRNA-212/132 Family is Involved in the Regulation of Long-Term Spatial Memory and Synaptic Remodeling
(2014-10-30)MicroRNAs are noncoding transcripts with crucial functions in probably every organ system. The roles of miRNAs in neuronal processes and cognitive functions are recently being appreciated. The discovery of neuronal activity ... -
New genetic mouse models for neurodegenerative diseases: Contribution of noradrenaline to Alzheimer’s disease pathogenesis and creation of a new genetic model for Parkinson’s disease.
(2011-12-15)Neurodegenerative diseases are among the most devastating diseases for which there are no cure to date. The greatest risk factor is advancing age. A common feature of these disorders is the toxic aggregation of a peptide ... -
Sleep control by TFAP2a and TFAP2b transcription factors in mice
(2023-01-31)Sleep is a universal behavior that exists across species. We previously found that deletion of transcription factor APTF-1 induces sleep loss in C. elegans and Drosophila. In mammals, sleep has two states: rapid eye movement ... -
Spatio-temporal Approach to Transport Dynamics in the Mammalian Ventricular System
(2015-02-19)This thesis addresses circadian regulation of solute transport systems in the brain ventricular system. It was found that transport of solutes between blood and the ventricular lumen are subjected to circadian regulation ... -
Spatio-temporal dynamics in the anchoring of cilia
(2019-10-02)The ventricular system of the mammalian brain consists of the two lateral, a third, and a fourth ventricle that interconnect and are filled with circulating cerebrospinal fluid (CSF) (1). CSF streams along the ventricular ... -
The Role of Lysine Acetyltransferase Tip60 in the Murine Hippocampus
(2015-07-07)Making new memories is a highly complex process, which involves rapid modifications of existing proteins, induction of gene expression, de novo protein synthesis, and the altering of neuronal structures. The cellular ...