Dokumente GGNB - Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und molekulare Biowissenschaften nach Gutachter "Mata, Ricardo Prof. Dr."
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Phosphoketolase - A mechanistic update
(2018-08-22)The thiamine diphosphate (ThDP)-dependent enzyme phosphoketolase catalyzes the phosphorolytic cleavage of fructose-6-phosphate and/or xylulose 5-phosphate under the generation of the high-energy metabolite acetyl phosphate, ... -
Reaction mechanism of hOMPD and CaAAD at atomic resolution
(2019-12-12)Decarboxylation reactions are fundamental processes in the chemistry of the animated world. Thus, the evolution of decarboxylases brought up a stunning array of diverse enzymes utilizing a variety of different mechanisms ... -
Structural interrogation of enzyme mechanism and dynamics
(2023-05-05)The pyruvate dehydrogenase complex (PDHc) is one of the largest macromolecular enzyme complexes, and serves an universally important metabolic function by converting pyruvate into acetyl-CoA. Therefore, the PDHc connects ...