Dokumente GGNB - Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und molekulare Biowissenschaften nach Gutachter "Raimundo, Nuno Dr."
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Lysosomal and mitochondrial crosstalk: the role of lysosomal signaling on mitochondrial biogenesis and function
(2018-11-15)Defects in metabolism result in various diseases, with neurodegeneration being one of the most prevalent consequences. Mitochondria and lysosomes are long known to be fundamental for cellular metabolism. In addition to ... -
Molecular mechanisms of synaptic vesicle recycling with a focus on Endophilin A and Rabconnectin-3a
(2019-11-01)Synaptic vesicle (SV) recycling at the synapse is fundamental to neurotransmission and it sustains unimpaired neuronal communication. It is a complex cell biological process, where the molecular steps are finely coordinated ... -
Neurovascular coupling in a central nervous system white matter tract
(2022-08-08)Neurovascular coupling is the process by which blood vessels dilate upon increased neuronal activity. It has been extensively studied in the murine grey matter and there are several models explaining possible molecular ... -
The role of alpha-synuclein on transcriptional deregulation in Parkinson’s disease
(2018-08-31)Parkinson’s disease (PD) is a complex neurodegenerative disorder that manifests through a broad ran ge of motor and non - motor symptoms. Alpha - synuclein (aSyn) is the major ... -
The role of mammalian TRC40 in membrane-protein targeting and chaperoning
(2019-05-24)Tail-anchored (TA) proteins are distinguished from other membrane proteins due to their particular topology. The best-characterized pathway for the targeting of TA-proteins is the GET pathway in yeast or the TRC pathway ...