Browsing GGNB - Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und molekulare Biowissenschaften by Referee "Schwappach-Pignataro, Blanche Prof. Dr."
Now showing items 1-4 of 4
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Reconstitution of Doa10-mediated ER-associated protein degradation with purified components
(2020-11-09)ER-associated protein degradation (ERAD) is a protein quality control pathway at the ER membrane mediated by membrane-embedded ubiquitin ligase complexes. During ERAD, membrane and luminal proteins are ubiquitinated and ... -
The client spectrum of Get3, an evolutionarily conserved chaperone of membrane proteins
(2020-03-12)Tail-anchored proteins constitute a physiologically important class of membrane proteins. Due to their topology, they are targeted post-translationally to membranes. Although Get3 is responsible for the membrane targeting ... -
Mechanisms of regulation of mitochondria-endoplasmic reticulum contact sites
(2019-11-19)In eukaryotic cells, inter-organelle communication is crucial for several cellular functions, as well as for several cell signaling mechanisms. Mitochondria and the endoplasmic reticulum (ER), for example, form tight contact ... -
The role of the mammalian GET pathway in the mouse liver
(2016-11-29)The correct insertion of membrane proteins is essential for the normal functioning of a eukaryotic cell, and different classes of membrane proteins employ different mechanisms of insertion into their target membrane. One ...