Browsing GGNB - Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und molekulare Biowissenschaften by Referee "Wörgötter, Florentin Prof. Dr."
Now showing items 1-20 of 22
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Development of new computational methods for non-invasive brain stimulation
(2014-07-21)In this thesis, we explore the use of computational models that numerically solve the electric field during TMS and tDCS in order to improve the spatial precision of these methods. For TMS, we validate the prediction of ... -
Drift and stabilization of cortical response selectivity
(2021-08-02)Synaptic turnover and long term functional stability are two seemingly contradicting features of neuronal networks, which show varying expressions across different brain regions. Recent studies have shown, how both of these ... -
Electrocutaneous stimulation to close the loop in myoelectric prosthesis control
(2017-08-09)Current commercially available prosthetic systems still lack sensory feedback and amputees are forced to maintain eye-contact with the prosthesis when interacting with their environment. Electrocutaneous stimulation is a ... -
Food Distribution in Ant Colonies: Trophallaxis and Self-Organization
(2017-09-14)Roughly one hundred million years ago, solitary insect species evolved social interactions that enabled the formation of colonies. A main reason for this advance was their ability to feed each other with previously ... -
Generation principles for arm movements in humans
(2012-06-14)This thesis comprises studies on the two major domains of motor control – posture and movement – with special focus on human upper limbs. Endeffector stiffness characterises the resistance of the arm against external ... -
Inducing Neuroplastic Changes in the Human Cortex using External Transcranial Electrical Stimulation Techniques
(2011-05-13)External transcranial stimulation tools have been widely used to investigate processes of neuroplastic induction and their underlying mechanisms in the intact human cortex. With the development ... -
Investigation of voltage- and light-sensitive ion channels
(2016-08-09)In this work, the properties of ion channels in biological membranes are characterized. Two systems are investigated: The conductance changes of the membrane of the axon initial segment (AIS) due to fast sodium channels, ... -
Manipulating neuronal communication by using low-intensity repetitive transcranial magnetic stimulation combined with electroencephalogram
(2021-11-18)Repetitive transcranial magnetic stimulation (rTMS) modulates ongoing brain rhythms by activating neuronal structures and evolving different neuronal mechanisms. In the current work, the role of stimulation strength and ... -
Modular Architecture for an Adaptive, Personalisable Knee-Ankle-Foot-Orthosis Controlled by Artificial Neural Networks
(2015-12-11)Walking is so fundamental in everyday life that it is, for most people, an unconscious action. Loss or limitations in the ability to walk or stand directly impair our mobility and independence. Reasons of limitations can ... -
Molecular and structural correlates of ocular dominance plasticity in mice
(2020-11-11)During early postnatal life, the brain goes through critical periods of increased plasticity, which enable experience-dependent refinements of neuronal circuits. Insertion of α-amino- 3-hydroxy-5-methyl-4-isoxazolepropionic ... -
Myoelectric Signal Processing for Prosthesis Control
(2015-02-03)The myoelectric signal (MES) is the electrical manifestation of contraction. The MES, recorded at the surface of the skin, has been exploited as a control source for powered upper limb prosthetics. The primary objective ... -
Numerical Simulations on the Biophysical Foundations of the Neuronal Extracellular Space
(2013-11-25)The electric activity of neurons creates extracellular potential fields. Recent findings show that these endogenous fields act back onto the neurons, contributing to synchronization of population activity. The influence ... -
On the Speed of Neuronal Populations
(2017-10-10)This thesis presents novel results in the areas of closed loop electrophysiology and neuronal population coding. This work begins by presenting the first known attempt to control the spike rate of a neuron or neurons using ... -
Peripheral nervous system control for neuroprostheses
(2017-09-21)Amputee patients who have lost a hand or arm are severely impaired in their daily life, as they lose the ability to grasp and interact with their environment. While the use of electromyographically controlled prosthetic ... -
Reading memory traces in cultured neuronal networks by probabilistic analysis
(2014-02-21)In this thesis, I am studying the enhancement of the collective burst dynamics, burst activation and propagation in hippocampal neuronal networks in-vitro by using optogenetic techniques. Channelrhodopsin-2 transfected ... -
Reconstructing the electrical dynamics on the heart
(2022-11-09)The heart is an electro-mechanical system. In 2010 about 4.25 million people died from cardiac arrhythmias. Immediate treatment in case of fibrillation is to shock the heart electrically with high energy to reset the ... -
Reference frames for planning reach movement in the parietal and premotor cortices
(2016-02-16)Human and nonhuman primates are able to plan and execute goal-directed behavior and flexibly respond to their surrounding stimuli. Their ability to adapt to changes in their environment is a crucial factor for their ... -
Simulation of fronto-parietal neural population activity to probe dimensionality reduction methods.
(2022-09-20)Recent developments of optical and electrophysiological recording tools allow the detailed capture of large neuronal populations. Findings show that their activity is constrained to a low-dimensional manifold within the ... -
Temporal information processing and memory guided behaviors with recurrent neural networks
(2015-02-25)The ability to quantify temporal information on the scale of hundreds of milliseconds is critical towards the processing of complex sensory and motor patterns. However, the nature of neural mechanisms for temporal information ... -
The Effect of Finite Temperature on the Jamming Transition
(2016-05-30)We study the effect of finite temperatures on spring networks obtained from amorphous, jammed packings of repulsive spheres. By means of a Monte Carlo Metropolis scheme, we analyse this two-dimensional model of an amorphous ...