dc.contributor.advisor | Alcarazo, Manuel Prof. Dr. | |
dc.contributor.author | Rugen, Christian Johann | |
dc.date.accessioned | 2022-05-31T13:42:56Z | |
dc.date.available | 2023-03-23T00:50:09Z | |
dc.date.issued | 2022-05-31 | |
dc.identifier.uri | http://resolver.sub.uni-goettingen.de/purl?ediss-11858/14077 | |
dc.identifier.uri | http://dx.doi.org/10.53846/goediss-9278 | |
dc.language.iso | eng | de |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | |
dc.subject.ddc | 540 | de |
dc.title | Towards a total synthesis of bazzanin K | de |
dc.type | doctoralThesis | de |
dc.contributor.referee | Alcarazo, Manuel Prof. Dr. | |
dc.date.examination | 2022-03-24 | de |
dc.description.abstracteng | Bazzanin K is a natural product from the group of macrocyclic bis-bibenzyls which was isolated from the liverwort bazzania trilobata. This work is dedicated towards the development of a synthetic strategy with bazzanin K at the end. Similar macrocyclic bis-bibenzyls have been prepared and their literature known syntheses shall serve as an inspiration. In a first step, unsubstituted model substances were prepared successfully to test the viability of pi-acid catalysis for the synthesis of a phenanthrene motif and an intramolecular Wittig reaction for a macrocyclization as key steps in the total synthesis. For the preparation of bazzanin K four aromatic building blocks were prepared with a variety of different substitution patterns. Different synthetic strategies for the connection of these units were tested and important key intermediates were obtained. | de |
dc.contributor.coReferee | Koszinowski, Konrad Prof. Dr. | |
dc.contributor.thirdReferee | Ackermann, Lutz Prof. Dr. | |
dc.contributor.thirdReferee | Janßen-Müller, Daniel Dr. | |
dc.contributor.thirdReferee | Steinem, Claudia Prof. Dr. | |
dc.contributor.thirdReferee | John, Michael Dr. | |
dc.subject.eng | bazzanin K | de |
dc.subject.eng | total synthesis | de |
dc.subject.eng | pi-acid catalysis | de |
dc.subject.eng | cross coupling reaction | de |
dc.subject.eng | aromatic compound | de |
dc.subject.eng | macrocyclization | de |
dc.subject.eng | Wittig reaction | de |
dc.subject.eng | macrocyclic bis-bibenzyl | de |
dc.identifier.urn | urn:nbn:de:gbv:7-ediss-14077-4 | |
dc.affiliation.institute | Fakultät für Chemie | de |
dc.subject.gokfull | Chemie (PPN62138352X) | de |
dc.description.embargoed | 2023-03-23 | de |
dc.identifier.ppn | 1806821869 | |