| dc.contributor.advisor | Harnisch, Lars-Olav Dr. | |
| dc.contributor.author | Müller, Marion | |
| dc.date.accessioned | 2022-10-11T09:05:37Z | |
| dc.date.available | 2022-10-18T00:50:07Z | |
| dc.date.issued | 2022-10-11 | |
| dc.identifier.uri | http://resolver.sub.uni-goettingen.de/purl?ediss-11858/14281 | |
| dc.identifier.uri | http://dx.doi.org/10.53846/goediss-9475 | |
| dc.language.iso | deu | de |
| dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | |
| dc.subject.ddc | 610 | de |
| dc.title | Langzeitfolgen bei ARDS-Patienten nach Lungenersatztherapie mit extrakorporaler Membranoxygenierung - Eine Pilotstudie zu Leistungsfähigkeit, Lebensqualität und Gesundheitszustand | de |
| dc.type | doctoralThesis | de |
| dc.contributor.referee | Mörer, Onnen Prof. Dr. | |
| dc.date.examination | 2022-10-11 | de |
| dc.description.abstracteng | Numerous follow-up studies exist regarding the acute respiratory distress syndrome (ARDS) as well as veno-venous extracorporeal membrane oxygenation (vvECMO), but a systematic follow-up of ADRS patients after ECMO therapy including physical and psychological examination, tests for quality of life, cognitive functions and post-traumatic stress disorder (PTSD) as well as an MRI-scan have not yet been described. In this prospective observational study 12 patients surviving ARDS after vv ECMO were examined. All 12 patients were able to lead a self-determined life and had been able to return to their former occupational field 5 - 32 months after ICU discharge (mean 16,5 months). The 36-Item Short Form Health Survey questionnaire (SF-36) showed a lower quality of life compared to the reference group in every category except general health (p = 0,857). The Impact of Events Scale-Revised (IES-R) questionnaire showed signs of PTSD in ten patients (83,3%). A modified Wechsler Memory Scale Test showed cognitive deficits compared to a healthy control group. The control group received better results in every category, four of seven sub categories showing significant results (logical memory I (p = 0,046) and II (p = 0,033), visual reproduction (p = 0,015) and spatial addition (p = 0,006)). Nerve impairments such as increased patella tendon reflex, impairments/lesion of N. cutaneus femoris lateralis on the cannulated extremity (50%) or paresis (14.3%) were found in the neurological examination. Ten patients received an MRI scan revealing cerebral hemorrhages, four patients (40%) showing microhemorrhages specifically in the splenium of the corpus callosum. | de |
| dc.contributor.coReferee | El-Essawi, Aschraf PD Dr. | |
| dc.subject.eng | ARDS | de |
| dc.subject.eng | ECMO | de |
| dc.identifier.urn | urn:nbn:de:gbv:7-ediss-14281-7 | |
| dc.affiliation.institute | Medizinische Fakultät | de |
| dc.subject.gokfull | Anästhesiologie / Intensivmedizin / Notfallmedizin / Analgesie - Allgemein- und Gesamtdarstellungen (PPN619875917) | de |
| dc.description.embargoed | 2022-10-18 | de |
| dc.identifier.ppn | 1818847914 | |
| dc.notes.confirmationsent | Confirmation sent 2022-10-11T09:15:01 | de |