dc.contributor.advisor | Schuh, Melina Dr. | |
dc.contributor.author | Charalambous, Chloe Amelia | |
dc.date.accessioned | 2022-10-13T08:42:27Z | |
dc.date.available | 2022-12-01T00:50:06Z | |
dc.date.issued | 2022-10-13 | |
dc.identifier.uri | http://resolver.sub.uni-goettingen.de/purl?ediss-11858/14289 | |
dc.identifier.uri | http://dx.doi.org/10.53846/goediss-9482 | |
dc.language.iso | eng | de |
dc.subject.ddc | 570 | de |
dc.title | Mechanisms of homologous chromosome synapsis and recombination in mammalian meiosis | de |
dc.type | doctoralThesis | de |
dc.contributor.referee | Dobbelstein, Matthias Prof. Dr. | |
dc.date.examination | 2020-12-02 | de |
dc.description.abstracteng | Homologous chromosome synapsis and recombination are key events that occur during
meiotic prophase and result in the formation of chromatin structures called chiasmata. These
chromatin structures physically connect homologous chromosomes, which in turn ensures
that each set of homologs are correctly segregated later in meiosis. During my PhD, I identified
novel aspects that promote the synapsis and recombination of homologs during mammalian
female and male meiotic prophase. In addition, I devised a new method that enables mouse
fetal oocytes to be studied through live-cell microscopy. The details of these findings are
discussed within this thesis. | de |
dc.contributor.coReferee | Behr, Rüdiger Prof. Dr. | |
dc.contributor.thirdReferee | Alim, Karen Dr. | |
dc.contributor.thirdReferee | Jakobs, Stefan Prof. Dr. | |
dc.contributor.thirdReferee | Steinem, Claudia Prof. Dr. | |
dc.subject.eng | Meiosis, Chromosome Synapsis, Meiotic Recombination | de |
dc.identifier.urn | urn:nbn:de:gbv:7-ediss-14289-5 | |
dc.affiliation.institute | Biologische Fakultät für Biologie und Psychologie | de |
dc.subject.gokfull | Biologie (PPN619462639) | de |
dc.description.embargoed | 2022-12-01 | de |
dc.identifier.ppn | 1818978679 | |
dc.identifier.orcid | 0000-0003-3649-7031 | de |
dc.notes.confirmationsent | Confirmation sent 2022-10-13T08:45:01 | de |