Prädiktive Parameter zu Mortalität und Häufigkeit von ICD-Schocks bei nicht selektierten ICD-Patienten

Parameters predictive of mortality and frequency of ICD shocks in unselected ICD patients

by Julian Frederick Schreckenberg
Doctoral thesis
Date of Examination:2023-02-28
Date of issue:2023-01-31
Advisor:Prof. Dr. Markus Zabel
Referee:Prof. Dr. Markus Zabel
Referee:PD Dr. Ulrich Krause
Persistent Address: http://dx.doi.org/10.53846/goediss-9691

 

 

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Abstract

English

Statements on mortality and appropriate events in a patient with an implantable cardioverter defibrillator are often the goal of investigations. However, predictive parameters for electrocardiogram intervals and specific T-wave morphologies have mostly only been described in a population without patients with an implantable cardioverter defibrillator. In this study, 1158 patients were included who had an implantable cardioverter defibrillator implanted at the University Hospital in Goettingen between December 4th, 1989 and October 1st, 2010 and who also had at least one electrocardiogram written during the course. New specific parameters of T-wave morphology such as T-wave dispersion and total cosine of all angles between QRS and T-vectors were calculated for 708 patients. The result shows predictive variables for the endpoints shock event and mortality, created for a group of patients with an implantable cardioverter defibrillator. Clinical variables and in particular special parameters of the T-wave morphology were included in these analyses. These results form the basis of further studies.
Keywords: ICD; The total cosine R-to-T; T-wave loop dispersion
Schlagwörter: ICD; T-Wellendispersion
 
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