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Der Einfluss von Δ9-Tetrahydrocannabinol und Cannabidiol auf die Pathologie des Morbus Alzheimer im Tg4-42hom-Mausmodell

dc.contributor.advisorBouter, Yvonne PD Dr.
dc.contributor.authorMaßmann, Malte
dc.date.accessioned2023-09-29T06:16:22Z
dc.date.issued2023-09-29
dc.identifier.urihttp://resolver.sub.uni-goettingen.de/purl?ediss-11858/14892
dc.identifier.urihttp://dx.doi.org/10.53846/goediss-10078
dc.format.extent92de
dc.language.isodeude
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subject.ddc610de
dc.titleDer Einfluss von Δ9-Tetrahydrocannabinol und Cannabidiol auf die Pathologie des Morbus Alzheimer im Tg4-42hom-Mausmodellde
dc.typedoctoralThesisde
dc.contributor.refereeBouter, Yvonne PD Dr.
dc.date.examination2023-10-12de
dc.description.abstractengThis thesis evaluates the histopathological effects of a long-term application of Cannabidiol and delta-Tetrahydrocannabiol in a mouse model of the sporadic Alzheimer`s disease in a preventive and therapeutic approach regarding histopathological markers of neuro-inflammation, neurogenesis, hippocampal neurodegeneration and expression of the CB1-Receptor. Whilst beneficial effects can be shown in the preventive approach of treatment, such can not be ascertained for the therapeutic approach of treatment.de
dc.contributor.coRefereeDresbach, Thomas Prof. Dr.
dc.subject.engAlzheimer`sde
dc.subject.engCannabidiolde
dc.subject.engTHCde
dc.subject.engTg4-42de
dc.identifier.urnurn:nbn:de:gbv:7-ediss-14892-5
dc.date.embargoed2024-09-29
dc.affiliation.instituteMedizinische Fakultätde
dc.subject.gokfullNeurologie - Allgemein- und Gesamtdarstellungen (PPN619876247)de
dc.subject.gokfullPsychiatrie (PPN619876344)de
dc.description.embargoed2024-09-29de
dc.identifier.ppn1867412845
dc.notes.confirmationsentConfirmation sent 2023-09-29T06:45:01de


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