dc.contributor.advisor | Bouter, Yvonne PD Dr. | |
dc.contributor.author | Maßmann, Malte | |
dc.date.accessioned | 2023-09-29T06:16:22Z | |
dc.date.available | 2024-09-29T00:50:09Z | |
dc.date.issued | 2023-09-29 | |
dc.identifier.uri | http://resolver.sub.uni-goettingen.de/purl?ediss-11858/14892 | |
dc.identifier.uri | http://dx.doi.org/10.53846/goediss-10078 | |
dc.format.extent | 92 | de |
dc.language.iso | deu | de |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | |
dc.subject.ddc | 610 | de |
dc.title | Der Einfluss von Δ9-Tetrahydrocannabinol und Cannabidiol auf die Pathologie des Morbus Alzheimer im Tg4-42hom-Mausmodell | de |
dc.type | doctoralThesis | de |
dc.contributor.referee | Bouter, Yvonne PD Dr. | |
dc.date.examination | 2023-10-12 | de |
dc.description.abstracteng | This thesis evaluates the histopathological effects of a long-term application of Cannabidiol and delta-Tetrahydrocannabiol in a mouse model of the sporadic Alzheimer`s disease in a preventive and therapeutic approach regarding histopathological markers of neuro-inflammation, neurogenesis, hippocampal neurodegeneration and expression of the CB1-Receptor. Whilst beneficial effects can be shown in the preventive approach of treatment, such can not be ascertained for the therapeutic approach of treatment. | de |
dc.contributor.coReferee | Dresbach, Thomas Prof. Dr. | |
dc.subject.eng | Alzheimer`s | de |
dc.subject.eng | Cannabidiol | de |
dc.subject.eng | THC | de |
dc.subject.eng | Tg4-42 | de |
dc.identifier.urn | urn:nbn:de:gbv:7-ediss-14892-5 | |
dc.affiliation.institute | Medizinische Fakultät | de |
dc.subject.gokfull | Neurologie - Allgemein- und Gesamtdarstellungen (PPN619876247) | de |
dc.subject.gokfull | Psychiatrie (PPN619876344) | de |
dc.description.embargoed | 2024-09-29 | de |
dc.identifier.ppn | 1867412845 | |
dc.notes.confirmationsent | Confirmation sent 2023-09-29T06:45:01 | de |