Short- and long-term quality of life in patients after surgically treated Spondylodiscitis
von Magdalena Barbara Moosmann geb. Krolikowska Flouri
Datum der mündl. Prüfung:2024-02-22
Erschienen:2024-02-13
Betreuer:Prof. Dr. Bawarjan Schatlo
Gutachter:Prof. Dr. Nicole von Steinbüchel-Rheinwall
Gutachter:Prof. Dr. Thomas Meyer
Dateien
Name:krolikowskaflouri_magdalena_dissertation1.pdf
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Zusammenfassung
Englisch
Background Spondylodiscitis affects a fragile patient population frequently fraught with severe comorbidities. Data on long-term outcomes, especially for patients undergoing surgery, are scarce. The aim of this study was to assess the long-term quality of life after surgical instrumentation. Methods Data of 218 patients who were treated for spondylodiscitis at our institution between January 2008 and July 2017 were reviewed. In-hospital death and mortality rates at 1 year and follow-up were assessed. A survey was conducted using the following questionnaires: Oswestry Disability Index (ODI), Short Form Work Ability Index (SF-WAI), 36-Item Short Form Health Survey (SF-36), and Short Form McGill Pain Questionnaire (SF-MPQ). We investigated the correlation between the assessed variables and clinical data including patient age, comorbidity score at admission, number of operated levels, corpectomy, and length of hospital stay. Results In-hospital mortality rate was 1.8% and 1-year mortality rate was 6.8%. At the final follow-up (mean 4,8 years), the mortality rate was 45.9%. Forty-four patients responded to the survey and had a mean age of 72 years. In the ODI questionnaire, disability grades were classified as minimal (23%), moderate (21%), severe (19%), complete (33%), and bed bound (4%). We found a significant correlation between inability to return to work and severe disability on ODI (p < 0.001), as well as a low score on any component of the SF-36 (p < 0.05). Conclusion Despite low in-hospital and 1-year mortality rates, patients with surgically treated spondylodiscitis are prone to long-term limitation in all domains of quality of life, especially in physical health and work ability.
Keywords: Quality of life; Oswestry Disability Index; Short Form Work Ability Index; 36-Item Short Form Health Survey; Short Form Mcgill Pain Questionnaire