Gravitationsventile in der ventrikuloperitonealen Shunttherapie: Retrospektive Analyse klinischer Einflussfaktoren

by Naima Madlen Diesner
Doctoral thesis
Date of Examination:2024-06-06
Date of issue:2024-06-03
Advisor:Dr. Florian Prof Stockhammer
Referee:Dr. Florian Prof Stockhammer
Referee:Dr. Ilko Prof Maier
Persistent Address: http://dx.doi.org/10.53846/goediss-10520

 

 

Files in this item

Name:DiesnerGravitationsventile.pdf
Size:7.26Mb
Format:PDF
Description:Dissertation: Gravitationsventile in der ventrikuloperitonealen Shunttherapie: Retrospektive Analyse klinischer Einflussfaktoren

The following license files are associated with this item:

Abstract

English

Gravitational valves (GV) prevent overdrainage in ventriculoperitoneal shunting. However, there is no data available on individually appropriate opening pressures in shunt systems when implementing a GV. Method: In order to determine predispositions for cerebrospinal fluid overdrainage in ventriculoperitoneal shunting, this retrospective study analyses ventriculoperitoneal shunt settings of GV combinations in an adult population. The vertical effective opening pressure (VEOP) is introduced as a new parameter to describe the opening pressure of all control devices used within an entire shunt system in upright body position while acknowledging deviations due to implant positioning. In absence of clinical symptoms related to under- or overdrainage, optimum VEOPs were defined for each patient and used to quantify possible factors related to individual shunt setting requirements. Results: 122 patients were eligible for this study. Higher VEOPs were found in females and patients under the age of 60 years. Mean VEOP was found to be high in idiopathic intracranial hypertension as well as malresoprtive and congenital hydrocephalus. Additionally, premenopausal women with a Body-Mass-Index above 25 kg/sqm showed a higher mean VEOP compared to their peers. Conclusion: Implantation of adjustable GV should be considered in female patients treated with ventriculoperitoneal shunting for pathology other than normal pressure hydrocephalus.
Keywords: hydrocephalus; ventriculoperitoneal shunt; gravitational valve; overdrainage
 
Statistik