Monozentrische Evaluation der ACR/EULAR-Myositis-Klassifikation 2017

Monocentric Evaluation of the 2017 ACR/EULAR Myositis Classification

by Kanan Hasanov
Doctoral thesis
Date of Examination:2025-07-10
Date of issue:2025-06-27
Advisor:Prof. Dr. Jens Schmidt
Referee:Prof. Dr. Jens Schmidt
Referee:Prof. Dr. Cornelia Sabine Seitz
Persistent Address: http://dx.doi.org/10.53846/goediss-11341

 

 

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Abstract

English

This retrospective, single-center study evaluates the applicability and diagnostic accuracy of the 2017 ACR/EULAR classification criteria for idiopathic inflammatory myopathies (IIM), comparing it to previous established classification systems. A total of 97 patients treated at the University Medical Center Göttingen between 2003 and 2020 were included, all with clinically and histologically confirmed IIM subtypes, including polymyositis, dermatomyositis, necrotizing myopathy, inclusion body myositis, and unclassified forms. The study assessed clinical, serological, imaging, and histopathological data. Statistical analysis revealed that while older classification systems had variable sensitivity, the ACR/EULAR criteria showed high reliability, practical applicability, and diagnostic performance, particularly in polymyositis and dermatomyositis. The study supports the implementation of the ACR/EULAR classification in clinical practice for improved diagnostic consistency.
Keywords: ACR/EULAR; Myopathies; Myositis; myositis-associated antibodies (MAA); dermatomyositis
Schlagwörter: Myositis; Myositiden; Statistik; Myositis Klassifkation
 
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