Browsing Zentren & Graduiertenschulen by Advisor & Referee "Fiala, André Prof. Dr."
Now showing items 1-20 of 29
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Learning-dependent plasticity of the Drosophila mushroom body: An optophysiological approach
(2024-07-29)Functional changes in the neuronal network of our brain enable experience-dependent adaptations to the environment through our behavior, referred to as learning and memory. One fundamental topic has occupied the neurosciences ... -
Neural circuit plasticity underlying learning and memory in Drosophila melanogaster: from synaptic connections to behavior
(2023-05-12)Understanding the principles behind olfactory higher-order associative chains formation in Drosophila is one step further into unraveling the essence of learning and memory. However, the rationale behind such mechanisms ... -
Context, circuit and modulation of courtship signal selection in Drosophila
(2023-03-23)Communication is multi-modal -- when we interact, we speak, gesticulate, and touch. However, the neural computations and circuits that select and coordinate these communication signals are unclear. We address this issue ... -
Network formation and reorganization of the olfactory system of Xenopus laevis
(2022-03-03)The olfactory system is a window to the chemical world, that permits each species to adapt to novel spaces and situations. Despite the various phylogenetic adaptations, this sensory system maintains similar functional and ... -
Neural Principles Underlying Learning and Memory in Drosophila melanogaster
(2021-03-19)The relay of information from external sensory organs to brain centres that ultimately control behavioural output dictates how an animal interacts with its environment. This process is integral to survival, allowing for ... -
Arrhythmia termination using Global Optogenetic Stimulation in ChR2 mice hearts
(2021-03-04)Cardiac arrhythmias represent a health threat worldwide that can end in sudden death. Treatments which include electrical shocks, anti-arrhythmic drugs and ablation show various disadvantages such as discomfort for the ... -
Plasticity of Dopamine-Releasing Central Brain Neurons Underlying Adaptational Feeding-Related Behavior in Drosophila Melanogaster
(2020-05-07)All organisms have to adapt and adjust behaviors to changing environmental conditions. Foraging and feeding behaviors are one of the most adaptive behaviors when changes in nutrient sources occur. Neuronal and behavioral ... -
Aberration correction in STED microscopy
(2019-11-21)In the last decade, superresolution microscopy techniques became a valuable tool to study sub-cellular structures with a resolution below the diffraction limit. The use of superresolution for brain research requires to ... -
Evolution of central complex development: Cellular and genetic mechanisms
(2019-11-11)Brains are conserved between insect species, as they consist of a set of anatomically similar areas, or neuropils. Simultaneously, these neuropils differ in size, shape, position and developmental timing between insect ... -
Nonlinearities in bipolar cells and their role for encoding visual signals
(2019-05-02)Vision begins in the retina, where ganglion cells separate the visual input into ~30 parallel output channels with different response characteristics to visual stimuli. How retinal ganglion cells obtain such a diversity ... -
Optical Analysis of Synaptic Plasticity Underlying Associative Learning in Drosophila melanogaster
(2018-10-10)Learning and memory is a prerequisite for the survival and the appropriate adaptation of behavioral responses in an ever-changing environment. Memories are formed, stored, and retrieved in the brains of animals. The formation ... -
Linking senses: the genetics of Drosophila larval chordotonal organs
(2018-08-06)Sensory systems have evolved in all organisms to detect changes in the environment or their internal state. Even though they are essential for fitness and survival, their phylogenisis is still unclear. The protosensory ... -
Developmental Studies on Eye Types and Pedipalps in Parasteatoda tepidariorum
(2017-12-21)Arthropods are by far the most species rich phylum in the animal kingdom and their evolutionary success is at least in part rooted in their diverse morphology. Despite these morphological differences, arthropods share a ... -
Analyzing receptor responses in the Drosophila Johnston's organ with two-photon microscopy
(2017-07-31)Hearing organs rely on force-gated ion channels to convert the mechanical energy imposed by sound into receptor potentials usable by the nervous system. So far, little is known about the identity and working mechanisms of ... -
Structural and functional characterisation of M/T cells using Ca2+ Imaging and Activity Correlation Imaging in dendritic networks of the developing Xenopus brain
(2016-12-19)Olfactory information collected in the nose is conveyed from the axon terminals of olfactory receptor neurons to the dendritic tufts of mitral/tufted (M/T) cells across glutamatergic synapses. These synaptic interactions ... -
Acetyltransferase TIP60/KAT5 regulates the Drosophila Circadian Clock
(2016-10-14)Endogenous clocks control behavioral and physiological processes in a rhythmic fashion exhibiting periodicity of ~24 h. Drosophila exhibits a robust rhythm in activity/rest patterns which is controlled by circadian pacemaker ... -
Probing roles of TRPML in Drosophila hearing
(2016-01-15)Several transient receptor potential (TRP) channels have been implicated in Drosophila hearing, including the TRPN channel NOMPC, the TRPVs Nan and Iav, and the TRPA members Pyx and Pain. Here I report that fly hearing ... -
Neuronal mechanisms of odor classification in the Drosophila antennal lobe: an optical imaging study
(2015-12-15)Drosophila senses diverse kinds of olfactory stimuli in the external environment. These stimuli are often not pure chemicals, but rather mixtures of many odorants. The fly olfactory system, however, needs to extract the ... -
A novel membrane-binding probe for the morphological and molecular characterization of synaptic vesicle recycling pathways
(2015-05-12)An important anatomical feature of neuronal synapses is the presynaptic bouton, a structure that isolates synaptic vesicle recycling from constitutive membrane trafficking pathways. However, in some neurotransmitter-releasing ... -
Computational modeling of neuronal circuits: heterogeneous connectivity and nonlinear transformation in olfactory processing
(2015-05-05)The first processing circuit in the olfactory system (antennal lobe or olfactory bulb) exhibits several astonishing nonlinear features, but how these characteristics emerge collectively in olfaction remains an open question. ...