Browsing Zentren & Graduiertenschulen by Advisor & Referee "Staiger, Jochen Prof. Dr."
Now showing items 1-13 of 13
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Chromatin remodeling BAF complex dependent mechanisms in development of cortical interneurons
(2025-10-21)GABAergic inhibitory neurons contribute to the excitatory and inhibitory balance in the brain. Dysfunction in GABAergic neuron development is implicated in various neurodevelopmental disorders. In recent years, the ... -
Understanding Visual Attention: A Multifaceted Approach
(2025-08-21)We all have an intuitive sense of what attention is, yet defining it precisely remains challenging. While research in psychology and neuroscience has explored its origins, mechanisms, and influence on behaviour for over a ... -
Molecular and circuit analysis of stable contrast processing in the visual system
(2022-08-01)Visual perception gives us a reliable estimate of the world throughout the day, thanks to the computations implemented in visual circuits. In a given space or time, the relative change in luminance, contrast, forms the ... -
Characterization of immune responses in the meninges
(2022-06-14)Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS), which is characterized by plaque-like demyelination in both white and grey matter and diffuse neurodegeneration. A T cell-driven ... -
Network formation and reorganization of the olfactory system of Xenopus laevis
(2022-03-03)The olfactory system is a window to the chemical world, that permits each species to adapt to novel spaces and situations. Despite the various phylogenetic adaptations, this sensory system maintains similar functional and ... -
Thalamocortical Innervation of GABAergic Interneurons in Mouse Primary Vibrissal Somatosensory Cortex
(2020-11-26)Interneurons utilizing gamma-aminobutyric acid (GABA) as primary neurotransmitter are thought to play a key role in neocortical processing. Their striking diversity has been in focus of numerous studies for decades. However, ... -
Molecular and structural correlates of ocular dominance plasticity in mice
(2020-11-11)During early postnatal life, the brain goes through critical periods of increased plasticity, which enable experience-dependent refinements of neuronal circuits. Insertion of α-amino- 3-hydroxy-5-methyl-4-isoxazolepropionic ... -
Cortical patterning and neuronal migration are under the guide of BAF complex functionality
(2020-03-26)The brain is one of the complex organs designed under the control of a plethora of molecular and cellular regulatory mechanisms, including transcriptional and epigenetic pathways. Brain organogenesis proceeds in a stepwise ... -
Nonlinearities in bipolar cells and their role for encoding visual signals
(2019-05-02)Vision begins in the retina, where ganglion cells separate the visual input into ~30 parallel output channels with different response characteristics to visual stimuli. How retinal ganglion cells obtain such a diversity ... -
BAF155 regulates the genesis of basal progenitors through both Pax6-dependent and independent mechanisms during cerebral cortex development
(2018-04-10)During mammalian development, the balance between symmetric and asymmetric division of radial glial (RG) progenitors regulates the tangential size versus radial growth of the cerebral cortex. The pool of basal progenitors ... -
Determination of the Dynamic Gain Function of Cortical Interneurons with distinct Electrical Types
(2017-04-25)In the living brain, individual neurons are constantly bombarded by thousands of synaptic inputs, which results in a fluctuating membrane potential. Neurons under such conditions are said to operate in a “fluctuation-driven ... -
Methodological and Cognitice Aspects of transcranial Electrical Stimulation
(2017-04-06)Transcranial electrical stimulation (tES) techniques are based on the external application of low-intensity electrical current to the brain. The external current can modulate cortical excitability by depolarizing or ... -
Order under the guise of chaos: functional neuroanatomy of the somatosensory "barrel" cortex of the reeler mutant mouse
(2016-05-13)Rodents possess an array of facial whiskers on either side of their snout, which they use to collect tactile information about their surroundings. In layer IV of the somatosensory cortex, individual whiskers are represented ...