Browsing Zentren & Graduiertenschulen by Advisor & Referee "Wichmann, Carolin Prof. Dr."
Now showing items 1-7 of 7
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Investigating the Ultrastructural Consequences of Aging on Murine Inner Hair Cell Ribbon Synapses
(2024-03-05)The ribbon synapses between inner hair cells (IHCs) and spiral ganglion neurons (SGNs) are first synapses of the auditory pathway. They mediate the harmonized and tireless neurotransmission needed for continuous sound ... -
Ultrastructural study of synaptic vesicle dynamics in murine inner hair cell ribbon synapses under sustained stimulation
(2023-07-11)Transmission of auditory information relies in the correct functioning of inner hair cell (IHC) rib-bon synapses, which mediate synaptic vesicle release in an indefatigable manner. The name-giving synaptic ribbon and the ... -
Mitochondrial adaptation at the neuronal presynapse
(2021-11-22)Synaptic transmission poses a major energy consuming process in the brain, but how neurons maintain a constant energy supply during extended synaptic activity and how presynaptic mitochondria contribute to the energy ... -
Aberration correction in STED microscopy
(2019-11-21)In the last decade, superresolution microscopy techniques became a valuable tool to study sub-cellular structures with a resolution below the diffraction limit. The use of superresolution for brain research requires to ... -
Structure and Mechanics of Neuronal Model Systems
(2019-11-15)Neurons of advanced animals need fast and efficient mechanisms to enable the functionality of a complex nervous system. In the life cycle of synaptic vesicles this is reflected in the endocytosis which generates new vesicles, ... -
Investigation of Vesicle Pool Dynamics at Activity Modulated Inner Hair Cell Ribbon Synapses
(2018-01-18)The inner hair cell ribbon synapses are the relay stations of the auditory pathway, attuned to transmit acoustic information at rates of up to hundreds of Hz. Such indefatigable signal transmission demands ultrafast vesicle ... -
Ultrastructural Characterization of The Output of VIP Expressing Interneurons in Mouse Barrel Cortex
(2017-11-15)Based on this preliminary result, a quantitative immunoelectron microscopy study was adopted to comprehensively characterize the output of VIP interneurons across the whole laminae of mouse barrel cortex. Using VIPcre/YFP ...