Closed Publications
Now showing items 21-31 of 31
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Die Bedeutung des Immunoproteasoms in der Behandlung epithelialer Thymustumoren
(2024-10-28)Thymic epithelial tumors are rare neoplastic diseases of the thymus and are divided into thymomas and thymic carcinomas based on their histopathological characteristics. Surgical tumor resection is the first choice of ... -
Der Effekt der H3.3K27M-Mutation auf die Antitumorwirkung von Curcumin
(2024-10-14)Diffuse intrinsic pontine glioma (DIPG) are pediatric high-grade glioma (pedHGG) with a median overall survival of 11 months after diagnosis. The aggressiveness of this tumor entity appears to be further increased in the ... -
Pankreatisch zystische Neoplasien und das orointestinale Mikrobiom: Evaluierung als Biomarker
(2024-09-24)Pancreatic cystic neoplasms (PCN) are mostly benign cystic lesions of the pancreas, which can be a precursor lesion for pancreatic cancer. The risk of malignancy varies widely, depending on the entity of the PCN. Despite ... -
Identifikation und Charakterisierung von Typ-II-Neuroblasten im Embryo des Mehlkäfers Tribolium castaneum
(2024-08-16)Evolution has created a wide range of morphological diversity in insect brains, while the basic structure is conserved. Little is known about the mechanisms that lead to this evolutionary diversification of similar structures. ... -
Bedeutung des G-Protein-gekoppelten Estrogen-Rezeptors 1 (GPER1) für die Progression des Vulvakarzinoms
(2024-06-20)The vulvar carcinoma is a gynecological tumor that primarily affects older women. It mostly comprises squamous cell carcinomas. The standard treatment typically involves a triple therapy of radiation, chemotherapy and ... -
Rolle des G-Protein-gekoppelten Östrogenrezeptors 1 (GPER1) beim Zervixkarzinom
(2024-03-21)Cervical cancer is the fourth most common cancer in women and after the mamma carcinoma the second most common gynecological carcinoma. The G-Protein-coupled Estrogen Receptor 1 (GPER1) is an important ubiquitous receptor ... -
Die Auswirkungen selektiver ERβ-Agonisten auf ERα-positive Brustkrebszellen hängen von den Expressionsniveaus der Östrogenrezeptoren ERα, ERβ und GPER1 und deren Regulation und Interaktion ab
(2023-12-04)Luminal A breast cancers represent the majority of all breast cancers and are more likely to recur and metastasise. In addition, resistance to tamoxifen is a major treatment problem and new therapeutic options are needed. ... -
Etablierung eines automatisierten Verfahrens zur Quantifizierung von Plasmakonzentrationen direkter oraler Antikoagulantien
(2023-10-12)More than a decade after their first approval, the imageability of direct oral anticoagulants (DOACs) still poses challenges to laboratories worldwide. Even though calibrator- and matrix-dependent chromogenic tests are now ... -
SUMOylierung in Nervenzellen und deren Regulation durch Sauerstoff und Glukose
(2023-04-27)Small ubiquitin-like modifiers (SUMO) are post-translational modifications (PTM) which, similar to Ubiquitin, are conjugated to specific target proteins. The conjugation is based on an energy-dependent enzymatic cascade, ... -
Zusammenhang der Biomarker NT-proBNP und Galectin-3 mit dem psychischen Befinden und der Lebensqualität von Patient*innen mit Herzinsuffizienz und erhaltener Ejektionsfraktion
(2023-04-17)Chronic heart failure is a complex clinical syndrome associated with high mortality, frequent hospitalizations, poor quality of life, and cost-intensive medical care. Based on ejection fraction, the clinical picture is ... -
Einfluss von GnRH Analoga auf die GLUT1 Expression in Ovarialkarzinomzellen und Rolle des GLUT1 Transporters im Tumorwachstum
(2021-08-26)Ovarian cancer is the leading cause of death in women diagnosed with gynecological cancers. Most of the cases are diagnosed at an advanced stage, which leads to poor outcomes of this disease. Chemotherapy makes the women ...