Browsing Human- und Zahnmedizin by Title
Now showing items 2404-2423 of 3000
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T1-Mapping des zervikalen Myelons bei degenerativer zervikaler Spinalkanalstenose
(2024-09-03)Cervical spinal canal stenosis is a common disease of the elderly and can cause a variety of symptoms. There are currently no standardised and clear treatment recommendations regarding the right treatment modality for ... -
Tabakentwöhnung als Ausbildungsziel im Medizinstudium
(2022-05-12)Smoking is associated with numerous diseases. The success rate of smoking cessation is enhanced by counselling; however, this is seldom carried out by physicians. A lack of training in undergraduate medical education was ... -
Tageszeitabhängige Abweichungen der statischen und dynamischen Okklusion
(2021-04-20)Introduction. Occlusion, i.e. the sum of contacts between teeth of the maxilla and mandible, plays a decisive role in the pathogenesis of temporomandibular disorders (tmd) and in restorative therapy. Static and dynamic ... -
Target recognition of an RNA methyltransferase
(2024-04-18)To date more than 150 different RNA modifications have been detected in cellular RNAs and are collectively termed the epitranscriptome. RNA modifications occur at different positions within each of the four bases or the ... -
Tau- und S-100b-Protein in der Differenzialdiagnose der bakteriellen Meningitis
(2012-09-14)In spite of intensive efforts towards an improved diagnostic and therapy the bacterial meningitis still shows a clinical picture to be taken seriously which ends for the affected patients not seldom with secondary damages ... -
Technische und biologische Komplikationen von einteiligen Zirkonoxidaufbauten und Vollkeramikkronen auf Einzelzahnimplantaten: 5-Jahresergebnisse einer retrospektiven klinischen Studie
(2014-08-14)This retrospective study evaluates the clinical outcomes of prefabricated one-piece zirconia abutments and all ceramic crowns in the anterior region over an observation period of five to seven years with closer examination ... -
Telemetrisch kontrollierte Blutdrucktherapie bei Patienten mit unzureichend eingestelltem Hypertonus
(2010-08-13)Introduction: Arterial hypertension represents the most common widespread disease because of its high prevalence and its mortality. Yet only approximately 30% of patients suffering from ... -
TGFbeta und Fibrose der Haut
(2021-06-29)Systemic sclerosis (SSc) is a fibrotic disease characterized by TGFβ-mediated differentiation of dermal fibroblasts to contractile myofibroblasts leading to accumulation of extracellular matrix proteins. Multiple studies ... -
The association between stress and blood pressure in a sample from the German Health Interview and Examination Survey for Adults (DEGS1)
(2015-07-14)Objective: Psychosocial stressors have long been studied for their contribution to the development of hypertension, but their role remains controversial. In this post-hoc analysis of the nationwide German Health Interview ... -
The DNA damage kinases MK2, Chk1 and the chromatin remodeling factor CHD8 determine the cellular outcome after replicative stress and DNA damage
(2021-03-26)DNA damage occurs and accumulates in every cell and is cause and consequence of cancerogenesis. Massive induction of exogenous DNA damage has its use in chemotherapy as it causes growth arrest and apoptosis in malignant ... -
The effect of acute evoked muscular pain at the lower back on motion capture and surface EMG during a repetitive movement task
(2022-05-24)Low back pain (LBP) is one of the most common reasons for consulting health care services. Since up to 80% of all people experience LBP at least once in their lifetime, it is of great interest to understand the underlying ... -
The effect of apomorphine on anodal tDCS-induced cortical plasticity in the human motor cortex
(2018-11-05)The aim of this thesis was to study the effect of apomorphine on non-focal anodal tDCS-induced plasticity and thus further examine the influence of the dopaminergic system on motor cortex plasticity in humans. In a randomized ... -
The effect of dimethyl fumarate on phenotype and function of B lymphocytes in MS patients
(2021-04-09)Although the oral agent DMF was approved for the treatment of RRMS in 2014 and demonstrably reduces relapse rates and disability progression, its effect on B cells, which are now thought to be major contributors to disease ... -
The effect of dopamine and its agonist pramipexole on oligodendrocytes in culture and in the cuprizone mouse model
(2014-02-10)Oligodendrocytes are of crucial importance for the integrity and function of the central nervous system (CNS) as well as for efficacy of signal conduction and thus for brain function itself. They are responsible for axonal ... -
The effect of glatiramer acetate on functional properties of B lymphocytes in patients with MS
(2021-11-29)Objective: We examined the effect of glatiramer acetate (GA) on B-cell maturation, differentiation, and antigen presentation in MS patients. Methods: A cross-sectional study of blood samples from 20 GA-treated and 18 ... -
The effect of Natalizumab on functional properties of monocytes in patients with Multiple Sclerosis
(2024-01-12)Natalizumab (NTZ), a monoclonal antibody against very late antigen-4 (VLA-4), is one of the most efficient therapies to prevent acute relapses in multiple sclerosis (MS). Since VLA-4 is a vital adhesion molecule for ... -
The Effects of Conventional Chemotherapeutics on the Activation of Type I Interferons (IFN-α/β) in Hepatic Cancer Cells in vitro: The Significance of Endogenous Type III Interferons (IFN-λ)
(2023-04-24)HCC is characterized by limited therapy options, poor response rates to systemic chemotherapy, and high lethality. Preclinical cancer models have revealed the efficacy of genotoxic drugs to rely on the release of type I ... -
The impact of expectation on patient-rated global effectiveness of total hip arthroplasty
(2022-11-28)Total Hip Arthroplasty (THA) is a standard elective surgery for hip osteoarthritis when reaching the limits of conservative medicine. Patient-based assessments are increasingly used for quality judgment after medical ... -
The influence of neprilysin on the pathogenesis of sporadic Alzheimer’s disease
(2024-05-16)The approach of this study was to examine the influence of neprilysin on the pathogenesis of sporadic Alzheimer’s disease. In three parts, this study combined standard histologic, immunohistochemical and in-vitro proteolysis ... -
The Inhibition of RNA-Polymerase II-Mediated Expression by the Non-Structural Protein NSs of the Oropouche Virus and Establishing an Oropouche Virus Minireplicon System
(2015-06-02)The OROV is a RNA virus that has a segmented, single stranded genome of negative polarity. It belongs to the Bunyaviridae family. Infection by the OROV causes an acute very debilitating febrile episode. This RNA virus is ...