Browsing Human- und Zahnmedizin by Title
Now showing items 1140-1159 of 3404
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Etablierung neuer immunhistochemischer Marker zur Unterscheidung von Plattenepithelkarzinomen der Lunge und des HNO-Traktes
(2021-05-06)Patients with head and neck squamous cell carcinoma (HNSCC) can develop both pulmonary metastases (metHNSCC) and metachronous primary squamous cell carcinomas of the lung (SQCLC) in the course of their disease. Despite the ... -
Die Etablierung normgerechter Schneidezahninklinationen – eine Überprüfung von potentiell relevanten Einflussfaktoren auf kephalometrische Zielgrößen
(2025-01-31)According to the results obtained in this retrospective in vivo study, neither the use of incisor brackets with torque differences of 10° (Roth vs. Ricketts brackets) nor the alternative use of 0.017x0.025 CNA finishing ... -
Etablierung und Charakterisierung einer Tetracyclin-induzierbaren PHD2-Knockdown-HeLa-Zelllinie
(2010-07-15)Prolyl-4-Hydroxylase Domain (PHD) enzymes 1-3 are oxygen-dependent enzymes, which hydroxylate the hypoxia-inducible factor (HIF) and target it for proteasomal degradation. HIF-1 is the ... -
Etablierung und Charakterisierung eines experimentellen Modells für invasive Gliome
(2018-04-04)Gliomas belong to the most malignant cancers we know. It is accepted that origin of the disease and glioma progression is caused by glioma-initiating cells (GICs). These cells have stem-cell attributes and are thought to ... -
“Etablierung und Charakterisierung eines humanen Zellmodells zur Erforschung der Pathophysiologie der Alternierenden Hemiplegie des Kindesalters”
(2025-10-06)Alternating hemiplegia of childhood (AHC) is a rare, severe neurological disorder characterized by transient episodes of hemiplegia combined with other paroxysmal symptoms such as dystonia, nystagmus, seizures, and autonomic ... -
Etablierung und Charakterisierung von Zervixkarzinomzelllinien mit stabiler Überexpression des G-gekoppelten Östrogenrezeptors (GPER1)
(2025-10-29)Cervical cancer (CC) remains the fourth most common malignancy among women worldwide, despite effective HPV vaccination strategies. CC can be classified into different histological subtypes. The majority of cases are ... -
Die Etablierung und Evaluation einer zahnärztlich-chirurgischen OSCE-Prüfung mit sechs Stationen in der ZMK-Klinik Göttingen - die Bewertung ärztlicher und studentischer Rater im Vergleich
(2017-11-27)Context: During the winter semester 2014/2015 the first formative OSCE in dental surgery took place at the Universitätsmedizin Göttingen in order to examine clinical skills as part of the dental surgery assessment. We ... -
Etablierung und Evaluation eines vereinfachten, speziesunabhängigen Anti-RVFV-Nukleoprotein-ELISAs
(2021-12-07)The Rift-Valley-fever-virus (RVFV) belongs to the family Phenuiviridae and is transmitted by insect bite. It is the causative agent of Rift Valley fever disease which affects livestock and humans in Africa and the Arabian ... -
Etablierung und Implementierung eines Qualitätsmamanagementsystems zur Einführung des Galileo-Vibrationstrainings mit Fokus auf die Patientenzufriedenheit
(2013-06-25)Since 2009, it has been a requirement for practising doctors and dentists to implement quality management (QM) in their surgeries. It was William Edwards Deming who originally laid the most significant foundation for quality ... -
Etablierung und Validierung der RNA-Interferenzmethode am Beispiel Apoptose-relevanter Gene
(2012-07-05)Specific inhibition of gene expression is becoming an increasingly important method for experimental strategies to influence tumor growth on a molecular level. In this work, we investigated the role of individual molecules ... -
Etablierung von Mutagenesemethoden zur pathophysiologischen Analyse der Signalaktivität in B-Lymphozyten
(2025-03-27)B cell receptor (BCR) signaling plays a crucial role in B cell activation, differentiation, and immune response. Dysregulation of this pathway is associated with various immunodeficiencies and B cell malignancies. This ... -
Etablierung von zirkulierenden DNA-Fragmenten als Biomarker für die klinische Progression einer Herzinsuffizienz mit erhaltener Ejektionsfraktion
(2020-02-21)Chronic heart disease is associated with abberant CpG promoter methylation, mechanistically involved cardiac fibrogenesis. Aberant CpG promoter methylation is equally reflected in corresponding blood samples („liquid ... -
Etablierung, Validierung und Anwendung einer gaschromatographisch-massenspektrometrischen Methode zur Analyse von Testosteron und 17α-OH-Progesteron im Serum
(2013-09-03)Objective: The objective of this study was to develop and validate a robust, specific and sensitive electron capture negative ionization gas chromatography-mass spectrometry method (GC-NCI-MS) to quantify serum testosterone ... -
Ethikberatung in der ambulanten Versorgung
(2017-09-04)BACKROUND: Clinical ethics consultation is proven and established in Germany and many other countries. Trained consultants support hospital-doctors in finding solutions for ethical conflicts occuring in the hospital. Ethics ... -
Ethische Aspekte der Schwangerschaftskonfliktberatung - Einschätzungen staatlich anerkannter Schwangerschaftskonfliktberaterinnen in Niedersachsen
(2012-06-05)This doctoral thesis gives an outline of the historical development of the abortion ban and the debate about the moral status of human embryos. The presentation of the results of the questionnaire survey is followed by the ... -
Ethische Aspekte der zahnärztlichen Behandlung von Palliativpatienten
(2016-02-15)The treatment of palliative patients by dentsts seem generally accepted as part of a interdisciplinary treatment. Whereas the planning and manufacturing of denture causes a discourse in the appraisal of its tenability. ... -
Ethische Aspekte von Demenzdörfern: Eine explorative Fokusgruppenstudie zur Sicht von Angehörigen, professionell Pflegenden und der breiteren Öffentlichkeit.
(2023-06-02)In terms of empirical informed ethics, the involvement of affected persons in the ethical discourse is necessary in order to allow their points of view to be considered in the ethical evaluation. This perspective is missing ... -
Die ethische Diskussion um Entscheidungen am Lebensende in Deutschland und Israel: Ein Kulturvergleich zu Einstellung und Handlungsmustern bei medizinischem Fachpersonal und Laien
(2014-10-21)This thesis surveys attitudes and practice of healthcare professionals and lay people regarding end-of-life decisions in Germany and Israel. Studies from 1990-2011 published in both countries were used for narrative ... -
Ethische Herausforderungen der COVID-19-Pandemie im internationalen Vergleich: Erkenntnisse aus 39 Expert*inneninterviews
(2025-03-06)Since spring 2020, the SARS-CoV-2 coronavirus has spread worldwide, causing profound medical, political, economic, cultural, and bioethical challenges in the ensuing pandemic. While the resulting conflicts initially appeared ... -
Ethische Implikationen der Prädiktion und Früherkennung einer Late-onset-Demenz
(2021-06-24)The focus on diagnosing dementia as early as possible has entered clinical practice, often supported by the use of an increasing number of available biomarkers. New diagnostics in this topic area are the subject of intense ...