Browsing Human- und Zahnmedizin by Title
Now showing items 1140-1159 of 3062
-
Expression und Funktion des Vitamin-D-Rezeptors in malignen Keimzelltumoren des Hodens
(2011-02-25)Testicular germ cell tumours (TGCT) are the most common malignancy in young men. They are clinical and histological subdivided in seminomas and non-seminomas. 1,25-dihydroxyvitamin D3 ... -
Expression und Wirkungsmechanismen von Gonadotropin-Releasing Hormon Typ II (GnRH-II) und seines Rezeptors in humanen Ovarial- und Endometriumkarzinomen
(2006-07-13)The majority of human endometrial- (>80%) and ovarian (>80%) cancer cell lines express gonadotropin releasing hormone (GnRH-I) and its receptor as a part of a negative autocrine/paracrine ... -
Expression von Genen des WNT-Signalwegs in humanen Makrophagen nach MCF-7 Ko-Kultivierung und in murinen Makrophagen nach Mikrovesikel-Stimulation
(2019-09-19)The interaction between malignant cells and stroma cells contributes in a crucial way to their biological activity. In breast cancer there is an association between activation of the canonical WNT-Pathway and aggressive ... -
Die Expression von High Mobility Group Box 1 (HMGB1) und dessen Receptor for Advanced Glycation Endproducts (RAGE) als Pathomechanismus der sporadischen Einschlusskörpermyositis
(2009-11-20)Sporadic inclusion body myositis (sIBM) is a chronic progressive muscle disease. In the tissue of sIBM patients degenerative molecules, inflammatory cells and cell stress molecules are ... -
Expression von HLA-Molekülen in humanen Monozyten in Abhängigkeit von Toxoplasma gondii-Infektionen
(2013-05-13)Toxoplasma gondii is an obligate intracellular protozoan parasite which infects a broad range of mammalian and avian hosts and which leads to lifelong persisting infections in humans and animals. For long-term survival in ... -
Expression von Lymphotaktin (XCL1) bei der Wegener'schen Granulomatose
(2012-03-27)OBJECTIVE: In Wegener's granulomatosis (WG), vasculitic lesions are characterized by prominent infiltration of polymorphonuclear neutrophils (PMN) and T cells, but underlying ... -
Expression von Peptidyl-prolyl cis/trans isomerase NIMA-interacting 1 (PIN1) in Blasten von Patienten mit akuter myeloischer Leukämie
(2011-06-20)Acute myeloid leukemia is a hematologic malignancy with fatal outcome within days or weeks if untreated. Even in the time of optimized, risk factor chemotherapy regimens for remission ... -
Expression von polyspezifischen Transportern in renalen Tumoren und ihre Bedeutung für die Chemotherapie
(2008-03-25)Renal cancer cell carcinoma (RCC) is usually chemoresistant. This chemoresistance would be overcome when a cytostatic is applied for which the RCC possesses an uptake transporter. In the present study I investigated the ... -
Expression von pro- und antiinflammatorischen Zytokinen in Kupfferzellen der Rattenleber unter Normal- und Entzündungsbedingungen
(2006-11-29)Lipopolysaccharides (LPS) as triggers of inflammation play an important role in the regulation of hepatic defence. The resident Kupffer cells (KC) of the liver respond directly to LPS by ... -
Expression von RANK / RANKL im Harnblasenkarzinom
(2015-12-03)Background: Bladder cancer causes significant health restrictions and burdens as a common disease, especially among men. The third most common localization for metastases of bladder cancer is the bone which often causes ... -
Expression von SDF-1/CXCL12 und CXCR4 in der sequenziellen DMBA-induzierten Karzinogenese des Hamsters
(2015-03-31)Mutual communication between chemokine stromal-derived-factor 1 (SDF-1/CXCL12) and the corresponding receptor CXCR4 may influence the motility, the tendency toward invasive growth, and the mode of metastasis of tumor cells. ... -
Die Expression von SRC vor und nach neoadjuvanter Radiochemotherapie im lokal fortgeschrittenen Rektumkarzinom cUICC II/III.
(2016-01-12)Purpose: SRC, one of the oldest proto-oncogenes, is encoding for the tyrosine kinase of the same name. The protein, which is localized in the cytosol as well as in the cell membrane, is involved in cell proliferation and ... -
Die Expression von Sulfattransportern als Funktion einer fortschreitenden Nierenfibrose am Modell der Alport-Maus
(2012-01-13)The system of sulfate metabolism and the expression of sulfate transporters in kidney and liver tissue are influenced by various parameters. The focus of this thesis lies on the sulfate ... -
Expressionsanalyse chondrogener Progenitorzellen im ex-vivo Migrationsexperiment
(2015-04-30)The chondrogenic progenitor cells are under control of the expression factors Sox9 and Runx2 favoritising either chondrogenic or osteogenic behavior. In this study we examine the impact on chondrogenic progenitor cells ... -
Expressionshemmung von MCM3 in Glioblastomen durch RNA-Interferenz
(2015-03-06)This work shows effects of specific suppression of MCM3-protein, which is upregulated in human glioblastoma cells (U87MG), by using RNAi. The effects on metabolic activity, cell viability, proliferation, cell cycle and ... -
Expressionsmuster von EBV mikroRNAs in Hodgkin Lymphomen
(2023-03-24)Epstein-Barr virus encodes 40 different miRNAs with considerable impact on cellular functions of the latently infected cell. In this study EBV miRNA expression patterns in EBV-positive Hodgkin lymphoma and other malignant ... -
Expressionsverhalten von ABC-A3 in Nicht-kleinzelligen Bronchialkarzinomen - ein neoadjuvantes Therapiekonzept
(2022-06-17)ATP-binding cassette transporter protein ABCA3 is known to be responsible for drug resistance. This respectively study examined the expression of ABCA3 as a possible predictive marker for a response to chemotherapy. The ... -
Das Expressionsverhalten von ABCA3 und TTF-1 in nicht-kleinzelligen Bronchialkarzinomen
(2016-08-15)Objectives: Clinical characteristics of non-small cell lung cancer (NSCLC) like poor outcome, high recurrence rates in low tumor stages and only temporary response to chemotherapy are caused by tumor cells with poorly ... -
Extendierte adjuvante Chemotherapie mit Temozolomid in der Behandlung maligner Gliome - Eine retrospektive Datenanalyse zur Wirksamkeit und Hämatotoxizität im klinischen Alltag
(2018-09-03)To receive a control over the efficiency as well as the compatibility of an extended temozolomide therapy, a retrospective analysis of data has been conducted in the context of this research. The data has been obtained out ... -
Extending the classical histological routine through microcomputed tomography imaging and multimodal image processing
(2024-04-08)Histological analysis has proven to be the de facto gold standard for the characterization of hard and soft tissue samples at cellular resolution in both clinical routine and biomedical research. After the tissue sample ...