Browsing Human- und Zahnmedizin by Title
Now showing items 1880-1899 of 3179
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Molekulare Determinanten zur sequenzspezifischen DNA-Bindung des Transkriptionsfaktors STAT1
(2018-01-09)STAT proteins (signal transducers and activators of transcription) play an essential part in one of the oldest and highly conserved signal transduction pathways. The JAK-STAT pathway transmits signals from many cytokines ... -
Molekulare Marker der frühen anterior-posterioren Achsenbildung im Kaninchen
(2021-06-16)During the early development of vertebrates, specific, morphological domains as signs of the developing anterior-posterior axis formation appear and define the body axes as the crucial step for Gastrulation and further ... -
Molekulare Mechanismen der antiproliferativen und antifibrotischen Wirkung von Mycophenolsäure in vitro
(2018-01-02)The aim of this study was to elucidate functional and molecular effects of mycophenolic acid (MPA) on non-lymphatic, kidney epithelial cells treated with transforming growth factor (TGF). MPA effects were studied using HK2 ... -
Molekulare Mechanismen des radiosensibilisierenden Effektes von Chloroquin beim Glioblastoma multiforme
(2013-10-16)Introduction: Glioblastoma multiforme (GBM) is the most aggressive brain malignancy. The clinical outcome remains disappointing, mainly due to inevitable GBM recurrence after postoperative radiation and chemotherapy. An ... -
Molekulare und elektrophysiologische Untersuchung der Exozytose in der Maus-Cochlea
(2023-12-20)The afferent synapses between inner hair cells (IHC) and spiral ganglion neurons are specialized to faithfully encode sound with sub-millisecond precision over prolonged periods of time. Here, I studied the role of Rab3 ... -
Molekulare Zellstressmechanismen bei der hereditären Einschlusskörpermyopathie
(2012-06-01)Mutations of the UDP-N-acetylglucosamine-2-epimerase/Nacetylmannosamine kinase (GNE)-gene have been demonstrated to be causally related to hereditary inclusion body myopathy (hIBM) (synonym: Nonaka Disease; distal ... -
Molekulargenetische Untersuchungen des SPG31-Gens bei der Hereditären Spastischen Paraplegie
(2014-10-21)The term hereditary spastic paraplegia describes a group of rare, clinically and genetically heterogeneous disorders. Until today more than 48 different genes have been identified whose variant forms lead to this clinical ... -
Molekulargenetische Veränderungen in nicht kleinzelligen Bronchialkarzinomen, detektiert durch komparative genomische Hybridisierung (CGH)
(2013-01-15)The knowledge of genomic changes in non small cell lung cancer (NSCLC) has been improved over the last decades but still little is known about the influence of chromosomal imbalances on the course of the disease. In ... -
Molekularpathologie seltener Sarkomentitäten des Urogenitaltraktes
(2013-11-07)Soft tissue sarcomas of the genito-urinary tract are really rare and aggressive tumors with rapid tumor progression and early metastatic disease. Despite the histological similarity of these small-, round- and blue cell ... -
Molekularzytogenetische Veränderungen bei kolorektalen Karzinomen und Lebermetastasen kolorektaler Karzinome
(2012-11-05)Colorectal carcinoma (CRC) is one of the most common malignant neoplasms in Germany. Most patients die due to metastases, whereas the liver is the most affected metastatic site. Nowadays scientists use molecularcytogenetic ... -
Morphologisch und Molekular studien der Keimblätter Differenzierung im frühen Saüger Embryo
(2009-11-20)In the mammalian embryo, too, germ layers and their precursors are useful for sorting the multitude of cells of the early embryo into well defined compartments and for tracing cell and ... -
Morphologische Charakterisierung von Wnt5a Knock-out-Mäusen: Eine licht- und elektronenmikroskopische Untersuchung des dermalen Lymphgefäßsystems
(2019-05-27)Lymphatic vessels are essential for the maintenance of tissue homeostasis. Their primary functions are the return of excessive tissue fluid into blood circulation, the transport of antigens both in soluble form and after ... -
Morphologische Normwerte von Augenmuskeln (M. levator palpebrae superioris und M. rectus superior) im Vergleich zu Extremitätenmuskeln (M. deltoideus und M. quadriceps femoris)
(2025-01-23)The function of the eye muscles enables them to perform fast and precise movements while also exhibiting a pronounced resistance to fatigue. Although the structure and function of eye muscles differ from the limb musculature, ... -
Morphologische Studien zu Veränderungen der Vaskularisation der Cochlea bei verschiedenen Formen der Schallempfindungsschwerhörigkeit
(2024-11-19)The objective of this work was the further development and implementation of methods for the qualitative and quantitative investigation of the fine-vascular structures of the lateral wall of the murine cochlea in presbycusis ... -
Morphologische und molekulare Untersuchungen zur Rechts-Links-Symmetriebrechung in Hühnerembryonen
(2021-02-18)Morphologische Asymmetrien entlang der Rechts-Links-Körperachse sind ein weit verbreitetes Phänomen im Tierreich. Bezüglich der Prozesse, die im symmetrisch angelegten Embryo zu den morphologischen Asymmetrien führen, ... -
Morphologische Veränderungen im Nucleus nervi facialis und im Motorkortex adulter Ratten nach Durchtrennung des Nervus facialis
(2011-10-19)The results of this study provide an insight into reorganization processes of nerve cell groups within the central nervous system (cortex) after peripheral Fazialisaxotomie in the rat. In ... -
Morphometrische und biomechanische Untersuchung der Sehnen-Knochen-Verbindung bei anatomischer Rekonstruktion der Rotatorenmanschette mittels der sogenannten Fadenbrücken-Technik am Tiermodell
(2011-10-04)Aim: The aim of the study was to evaluate a suture-bridge technique for rotator cuff repair by reference to the time zero mechanical and footprint properties in an animal model.Method: ... -
Morphometrische Wirbelkörperveränderungen bei Kindern mit spinaler Muskelatrophie und bilateralen vertikal-expandierbaren Wirbelsäulenimplantaten
(2022-11-22)Treatment of progressive spinal deformities in children and adolescent with vertical expandable spinal implants can often avoid early spinal fusion with adverse effects on thoracic and lung development during the growth ... -
Morphometrischer Vergleich der Gewebeveränderung bei Weichgewebedissektion mit dem Ultraschallskalpell und monopolarer Elektrokoagulation
(2014-02-04)Background Ultrasonic scalpel (UC) and monopolar electrocautery (ME) are common tools for soft tissue dissection. However, morphological data on the related tissue alteration are discordant. We developed an automatic ... -
MR-tomografisches Langzeit-Follow-up GH-produzierender Hypophysenadenome unter Pegvisomant-Therapie. Eine prospektive Studie.
(2011-01-31)In addition to previously available therapies, pegvisomant offers a new treatment of acromegaly. Therefore computer aided volumetry is of particular importance. It is crucial to screen out ...