Browsing Human- und Zahnmedizin by Title
Now showing items 1883-1902 of 3249
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MicroRNA-Regulation in experimenteller autoimmuner Enzephalomyelitis im Vergleich mit Multiple Sklerose-Läsionen
(2014-09-08)Multiple sclerosis (MS) is the most common chronic inflammatory disease of the central nervous system and the most common cause of acquired disability in young adults. Histopathological hallmarks of MS are focal lesions ... -
MicroRNAs, p16- und HPV-Status und transorale Lasermikrochirurgie im multimodalen Behandlungskonzept bei Oropharynxkarzinomen
(2023-11-08)Carcinomas of the head and neck region are worldwide among the most common malignant diseases. Of these, around 12 - 14% are oropharyngeal carcinomas. Transoral CO2-laser microsurgery is a less invasive procedure, which ... -
Das Migrationsverhalten von Brustkrebszellen unter Einfluss von Wnt-Signaling
(2016-01-25)Focus of this study was the aspect of migration of epithelial cells on an almost physiological matrigel-coated surface. In a cell culture assay the migratory potential of the weakly invasive cell line MCF-7 was analyzed. ... -
Mikro CT-, Histomorphometrische- und Immunhistologische Analyse 3D gedruckter PLLA/CaCO3- Scaffolds mit Zusatz von CaPO4 im Göttinger Minipig zur Entwicklung eines patientenspezifischen, resorbierbaren Knochenersatzmaterials
(2025-06-12)Introduction: One of the central challenges in oral and maxillofacial surgery is the reconstructive restoration of tissue defects following extensive tumor resections in the head and neck region. Microvascular free tissue ... -
Mikro-RNA-Expression bei der Einschlusskörpermyositis
(2023-08-16)The chronic disease inclusion body myositis belongs to the inflammatory myopathies and is the most common in older age. Muscle weakness and atrophy affect the quality of life of patients. Diagnosis can be made on the basis ... -
Mikrobielle Kontamination intravenöser Anästhetika im Kreislaufmodell unter Verwendung der Göttinger Konfiguration eines TIVA-Sets
(2011-12-21)BACKGROUND: Nonsterile handling of propofol for anesthesia has been linked with severe sepsis and death. Placing a single check valve in the IV tubing does not prevent retrograde ... -
Mikrobiologische Diagnostik bei periimplantären Erkrankungen – ein Vergleich von PCR und Real-time PCR
(2015-04-17)With the increasing number of dental implants, peri-implant diseases are coming to the fore. By the introduction of commercial microbiological testing in periodontal di-seases the expectation of a diagnostic benefit was ... -
Mikroglia fördert die Invasivität von Karzinomzellen
(2009-12-15)Brain metastases are the most prevalent tumors of the CNS and predominantly deriving from lung and breast cancer. CNS metastasis is increasing due to impaired primary therapy, however, ... -
Mikroglia-/Makrophagenphänotypen bei humanen Entmarkungserkrankungen (MS, NMO und PML)
(2022-12-14)Multiple sclerosis (MS) is a demyelinating disease of the central nervous system with unknown pathophysiology. Microglia and macrophages accumulate in MS lesions and are discussed as initiators of the cascade of ... -
Mikroglia-Aktivierung durch Bestandteile von <i>Borrelia burgdorferi sensu lato</i>
(2015-04-15)Lyme disease is the most commonly reported vector-borne illness. It is caused by bacteria of the Borrelia family and transmitted by infected ticks. The outer surface protein C (OspC) and the flagellar protein p41 are common ... -
MikroRNA-146a-basierte Mechanismen vaskulärer Fibrose im Kontext der arteriellen Gefäßversteifung
(2022-10-05)Age-related arterial stiffening is both a serious cardiovascular disease and a risk factor in its own for other cardiovascular diseases. The underlying pathological mechanisms are the subject of current research. In ... -
Mikrosatelliteninstabilität (MSI) in Rektumkarzinomen vor und nach Chemoradiotherapie
(2012-05-16)Colorectal carcinomas are the second most common cancers in Germany. Spontaneously occurred gene damages as well as hereditary acquired gene damages may cause cancer. Analyses for MSI are performed as standard in the ... -
Milde therapeutische Hypothermie als Konzept in der Versorgung nach kardiopulmonaler Reanimation ( Postresuscitation Care ) - Prädiktoren für das Überleben oder eine gute neurologische Prognose
(2018-08-10)Sudden cardiac death is among the most common causes of death in Central Europe with high mortality and poor prognosis, especially in non-cardiac cause. An important positive predictor of survival is the presence of ... -
miR-125 regulates niche organization in Drosophila melanogaster ovary by affecting Notch signaling pathway via its target Tom
(2015-08-11)For the maintenance of tissue homeostasis upon injury or natural cell turnover, a constant source of new cells is needed. Usually these cells are delivered by tissue specific adult stem cells. ... -
Mit AML assoziierte MLL-partielle Tandemduplikationen (MLL-PTD) sind in Stammzellen aus Nabelschnurblut lebenslang nachweisbar
(2010-05-21)AML-associated MLL-PTD have an impact on leukemogenesis by a gain of function and confer an unfavorable prognosis. They are also present in healthy adults and children. We tracked down ... -
Mitochondriale Dynamik und Funktion in der Muskelentzündung
(2021-09-30)In muscle biopsies of patients with inclusion body myositis signs of degeneration, inflammation and mitochondrial damage can be detected. Pathogenesis of this neuromuscular disorder, predominantly affecting elderly male ... -
Mitochondriale Redoxhomöostase in hippocampalen Neuronen MeCP2-defizienter Mäuse
(2019-09-11)This work should address the question of whether mitochondrially-generated ROS are the possible cause of neuronal dysfunction in RTT. Data collected in previous studies suggest that oxidative stress is important for the ... -
Mitomycin/Cisplatin oder Mitomycin/Vinorelbin und Erythropoetin als Therapie bei vorbehandelten Patienten mit Rezidiv eines NSCLC innerhalb des Bestrahlungsfeldes
(2010-10-13)Background: Cisplatin-based chemotherapy in combination with thoracic radiotherapy is frequently used as standard treatment for patients with unresectable NSCLC stage IIIA/IIIB disease. ... -
Mittelfristiger Einfluss der Vitrektomie bei Makulaerkrankungen auf den Augeninnendruck
(2019-01-21)Purpose: To determine if pars plana vitrectomy for macular hole and epiretinal membrane, decreased intraocular pressure (IOP) of the vitrectomized eye in comparison to the non-operated eye (control group). Methods: In ... -
MMSE-Präprogressionsrate als potentieller Prädikator des kognitiven und funktionellen Progresses der Alzheimer-Demenz
(2017-05-22)For many years studies tried to predict the progress of Alzheimer’s disease (AD), but until finishing this work no examination techniques have reached the clinical stage. The preprogression rate (PPR) was first mentioned ...