Browsing Human- und Zahnmedizin by Title
Now showing items 1903-1922 of 3270
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Mikrobiologische Diagnostik bei periimplantären Erkrankungen – ein Vergleich von PCR und Real-time PCR
(2015-04-17)With the increasing number of dental implants, peri-implant diseases are coming to the fore. By the introduction of commercial microbiological testing in periodontal di-seases the expectation of a diagnostic benefit was ... -
Mikroglia fördert die Invasivität von Karzinomzellen
(2009-12-15)Brain metastases are the most prevalent tumors of the CNS and predominantly deriving from lung and breast cancer. CNS metastasis is increasing due to impaired primary therapy, however, ... -
Mikroglia-/Makrophagenphänotypen bei humanen Entmarkungserkrankungen (MS, NMO und PML)
(2022-12-14)Multiple sclerosis (MS) is a demyelinating disease of the central nervous system with unknown pathophysiology. Microglia and macrophages accumulate in MS lesions and are discussed as initiators of the cascade of ... -
Mikroglia-Aktivierung durch Bestandteile von <i>Borrelia burgdorferi sensu lato</i>
(2015-04-15)Lyme disease is the most commonly reported vector-borne illness. It is caused by bacteria of the Borrelia family and transmitted by infected ticks. The outer surface protein C (OspC) and the flagellar protein p41 are common ... -
MikroRNA-146a-basierte Mechanismen vaskulärer Fibrose im Kontext der arteriellen Gefäßversteifung
(2022-10-05)Age-related arterial stiffening is both a serious cardiovascular disease and a risk factor in its own for other cardiovascular diseases. The underlying pathological mechanisms are the subject of current research. In ... -
Mikrosatelliteninstabilität (MSI) in Rektumkarzinomen vor und nach Chemoradiotherapie
(2012-05-16)Colorectal carcinomas are the second most common cancers in Germany. Spontaneously occurred gene damages as well as hereditary acquired gene damages may cause cancer. Analyses for MSI are performed as standard in the ... -
Milde therapeutische Hypothermie als Konzept in der Versorgung nach kardiopulmonaler Reanimation ( Postresuscitation Care ) - Prädiktoren für das Überleben oder eine gute neurologische Prognose
(2018-08-10)Sudden cardiac death is among the most common causes of death in Central Europe with high mortality and poor prognosis, especially in non-cardiac cause. An important positive predictor of survival is the presence of ... -
miR-125 regulates niche organization in Drosophila melanogaster ovary by affecting Notch signaling pathway via its target Tom
(2015-08-11)For the maintenance of tissue homeostasis upon injury or natural cell turnover, a constant source of new cells is needed. Usually these cells are delivered by tissue specific adult stem cells. ... -
Mit AML assoziierte MLL-partielle Tandemduplikationen (MLL-PTD) sind in Stammzellen aus Nabelschnurblut lebenslang nachweisbar
(2010-05-21)AML-associated MLL-PTD have an impact on leukemogenesis by a gain of function and confer an unfavorable prognosis. They are also present in healthy adults and children. We tracked down ... -
Mitochondriale Dynamik und Funktion in der Muskelentzündung
(2021-09-30)In muscle biopsies of patients with inclusion body myositis signs of degeneration, inflammation and mitochondrial damage can be detected. Pathogenesis of this neuromuscular disorder, predominantly affecting elderly male ... -
Mitochondriale Redoxhomöostase in hippocampalen Neuronen MeCP2-defizienter Mäuse
(2019-09-11)This work should address the question of whether mitochondrially-generated ROS are the possible cause of neuronal dysfunction in RTT. Data collected in previous studies suggest that oxidative stress is important for the ... -
Mitomycin/Cisplatin oder Mitomycin/Vinorelbin und Erythropoetin als Therapie bei vorbehandelten Patienten mit Rezidiv eines NSCLC innerhalb des Bestrahlungsfeldes
(2010-10-13)Background: Cisplatin-based chemotherapy in combination with thoracic radiotherapy is frequently used as standard treatment for patients with unresectable NSCLC stage IIIA/IIIB disease. ... -
Mittelfristiger Einfluss der Vitrektomie bei Makulaerkrankungen auf den Augeninnendruck
(2019-01-21)Purpose: To determine if pars plana vitrectomy for macular hole and epiretinal membrane, decreased intraocular pressure (IOP) of the vitrectomized eye in comparison to the non-operated eye (control group). Methods: In ... -
MMSE-Präprogressionsrate als potentieller Prädikator des kognitiven und funktionellen Progresses der Alzheimer-Demenz
(2017-05-22)For many years studies tried to predict the progress of Alzheimer’s disease (AD), but until finishing this work no examination techniques have reached the clinical stage. The preprogression rate (PPR) was first mentioned ... -
Das Modell des partizipativen Kinderkrankenhauses - Systematische Analyse der Methoden der Partizipation in der stationären Versorgung von Kindern und Jugendlichen
(2021-02-22)The background of this doctoral thesis is the Convention on the Rights of the Child, which was adopted in 1989. In addition to protection and care, children are granted the right to participation, or more precisely, the ... -
Modelle hausärztlicher Versorgung im Meinungsbild der Bevölkerung
(2001-07-27)Background: Strengthening the "gatekeeping" function of primary care physicians by encouraging first-contact care and coordinating the use of specialist services ma be an importan issue for Germa er, there ... -
Modifikation des Hypertrophie-Phänotyps der Myosin-Bindungs-Protein-C defizienten Maus durch Muscle-LIM-Protein
(2011-02-18)Modification of the hypertrophy-phenotype in Myosin-Binding-Protein-C-deficient mice by Muscle-LIM-Protein Approximately 3% of all citizens in the old West German States are affected by ... -
Modifikation und Analyse der allogenen extrakorporalen Photopherese im Mausmodell der Graft-versus-Host Disease
(2023-01-31)Extracorporeal photopheresis (ECP) is a well-established and well tolerated second line therapy in graft-versus-host disease (GvHD), a major cause of high morbidity and mortality after a hematopoietic stem cell transplantation. ... -
Modulation der Hitzesensitivität im Prostatakarzinom in vitro: Der Einfluss der Androgenachse
(2022-10-13)Focal therapies are becoming increasingly important in the treatment of prostate cancer as an intermediate solution between definitive treatment options for localized prostate cancer and active surveillance. Many focal ... -
Modulation der Hypoxie-Empfindlichkeit medullärer Netzwerke in einem Maus-Modell des Rett-Syndroms
(2012-09-14)For this thesis I investigated if elicitation of hypoxia-induced spreading depression-like depolarizations (HSDs) in the brain stem of mice is possible. Furthermore I screened for differences in hypoxia susceptibility between ...