Browsing Human- und Zahnmedizin by Title
Now showing items 2131-2150 of 3249
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Die pH-Abhängigkeit des NaDC3-Transporters
(2017-11-27)The sodium-dependent dicarboxylate transporter 3 (NaDC3) is located close to organic anion transporters (OAT) in the basolateral membrane of renal proximal tubule cells. The transport-activity of OAT1 (p-aminohippurate) ... -
Eine Phantomstudie zur Strahlenexposition des Untersuchers bei Rotationsaquisitionen mit einer Flachdetektor-Angiographie-Anlage
(2014-07-21)In addition to the conventional digital subtraction angiography (DSA), rotation angiographies and DYNA-CTs have been implemented particularly since the introduction of angiographic systems using flat-panel detector technology. ... -
Pharmakogenetische Untersuchungen beim Hausarzt aus Sicht von Patienten
(2008-11-24)Background: Pharmacogenetic testing could, in the future, help gauge the effects, adverse side effects and necessary dosage of a medication prior to consumption. The aim of this study was ... -
Die Pharmakokinetic von Meropenem bei Patienten mit schweren Infektionen
(2010-08-04)Meropenem is a carbapenem antibiotic with a broad antibacterial spectrum, good tolerability and high penetration into infected tissues. Due to its excellent pharmacokinetic and pharmacodynamic ... -
Pharmakokinetik von Doxorubicin: Populationsvariabilität und Einfluss von genetischen Polymorphismen in Membran-Trasportproteinen
(2007-08-02)In this thesis, the impact of genetic polymorphisms of the membrane transporters MDR1, MRP1, MRP2, MRP3 and BCRP on the pharmacokinetics and side effects of doxorubicin of 94 non-pretreated ... -
Pharmakologische Behandlung von stationären Patienten mit einer emotional instabilen Persönlichkeitsstörung
(2016-03-08)Disease-related deficits in the everyday social interaction are responsible for socially inadequate integration of patients with borderline personality disorder (BPS). The supply resources due to the extensive psychosocial ... -
Pharmakologische Charakterisierung der purinergen Rezeptoren der Stützellen der olfaktorischen Mukosa des larvalen Xenopus laevis
(2011-04-06)Extracellular purines and pyrimidines are important signaling molecules acting via purinergic receptors. In the present work ATP-induced responses in sustentacular supporting cells of ... -
Pharmakologische Inhibition von Rho-Kinase im Mausmodell der Amyotrophen Lateralsklerose
(2015-06-12)Since the development of Riluzol no substance, which had been successfully tested in a preclinical setting before, has been able to be successful as a disease modifying drug in human ALS although there has been enormous ... -
Pharmakologische rho-Kinasen-Inhibition im H4-Zelllinien-Modell des Morbus Parkinson
(2024-04-26)Parkinson's disease (PD) is the most common neurodegenerative movement disorder, unfortunately there are no curative therapeutic approaches to date. Rho-associated protein kinase (ROCK) has been described as a novel ... -
Phäno- und genotypische Charakterisierung konsekutiver Isolate eines Patienten mit rezidivierenden Clostridium difficile-Infektionen
(2019-03-06)Thirteen C. difficile isolates deriving from recurrent infections of a single patient were isolated during a fifteen-month ongoing course of disease and analyzed regarding their morphology, phenotype and genotype. The ... -
Phänotyp-Analyse und Genotyp-Phänotyp-Assoziationen bei 83 mit FOXG1-Syndrom
(2019-05-13)Purpose: The aim of this study was to increase the knowlegde about the clinical spectrum and to evaluate genotyp-phenotyp associations in FOXG1 syndrome due to FOXG1 variants. Methods: We recruited 30 new and 53 reported ... -
Phänotypische Charakterisierung humaner Monozyten von Blutspendern mit chronischer Toxoplasmose und nicht-infizierten Kontrollen
(2020-11-13)The globally distributed parasite Toxoplasma gondii (T. gondii) is an obligatory intracellular protozoan and the infectious agent of toxoplasmosis in humans and animals. Humans become regularly infected by ingestion of ... -
Phänotypische und funktionelle Charakterisierung der kutanen Immunantwort bei Kontakt mit Natriumlaurylsulfat
(2025-02-14)Sodium lauryl sulfate (SLS) is regularly used as a so-called irritancy control in patch testing in the allergological diagnosis of contact allergies and we encounter it in everyday life, for example in soaps, cleaning ... -
Physical activity and developmental psychopathology in children and adolescents: cross-sectional, longitudinal follow-up and concurrent developmental relationships
(2023-09-26)The current cumulative dissertation aimed to investigate the cross-sectional and longitudinal relationships between mental health problems, including symptoms of ADHD, and physical activity (PA) in children and adolescents. ... -
Physikochemische und bioaktive Eigenschaften von mit Methacryl-funktionalisierten Silica-Nanopartikeln modifizierten experimentellen Adhäsiven
(2020-05-25)Aim: The aim of the study was to investigate the physico-chemical and bioactive properties of experimental dental adhesives containing methacryl-functionalized polyhedral oligomeric silsesquioxane (MA-POSS-8). Methods: ... -
Physiologische und morphologische Charakterisierung des dopaminergen Systems in der olfaktorischen Peripherie von Xenopus-laevis-Larven
(2013-11-18)It has been shown in many studies, that dopamine plays an important role in the olfactory system. In the current study I was examining the physiological and morphological characteristics of the dopaminergic system in the ... -
Pilotstudie zur Allergieprävention in weiterführenden Schulen
(2019-10-22)In 2009 a working group of the Institute of Occupational, Social and Environmental Medicine from the University Medical Center Göttingen realized a project for the initiation and evaluation of allergy prevention at schools. ... -
Pioneering studies on the gene order, DNA sequence and evolution of the MHC class I region in the new world primate Callthrix jacchus
(2007-08-02)Analysis of MHC class I region in common marmoset (Callithrix jacchus) was made with 42 BAC clones. These clones containing class I region genes were identified for the purpose of ... -
Placebokontrollierte, doppelblinde Crossover-Studie zur Untersuchung der Wirkung einer parenteralen Gabe von Pantoprazol auf die Kontraktilität des Herzen
(2015-03-18)Purpose: Reports on cardiac problems with oral proton pump inhibitors have caused extensive safety reviews by the US Food and Drug Administration. We provide addi- tional data on acute cardiac effects of an intravenous ...