Browsing Human- und Zahnmedizin by Title
Now showing items 2136-2155 of 3378
-
Optical Measurement of Glutamate Release at a Fast Central Synapse
(2025-04-02)Recent advances in the development optogenetic indicators have enabled optical measurements of neurotransmitter release and dynamics in the synaptic cleft. The precise information about spatial and temporal neurotransmitter ... -
Optimierte expressionsbasierte Mikrodissektion an Formalin-fixiertem Gewebe des Adenokarzinoms der Lunge
(2021-04-13)In precision medicine of tumors, the analysis of specific DNA alterations is crucial for targeted therapy. Lung cancer represents a prototypical example and is also one of the leading causes of cancer-related deaths ... -
Optimierung der molekularbiologischen Diagnostik systemischer Mykosen
(2012-05-15)The rapid and efficient diagnosis of systemic fungal infections is essential for an effective therapeutic regimen of frequent immunosuppressed patient population. For this purpose, the PCR method offers a good diagnostic ... -
Optimierung der Rotationsausrichtung der femoralen Implantatkomponente in der Kniegelenksendoprothetik mit bandspannungsbasierter Navigation
(2013-09-13)Femoral malrotation in total knee arthroplasty is correlated to an increased number of revisions. Bony landmarks such as Whiteside line, posterior condyle axis and transepicondylar axis are used for determining femoral ... -
Optimization of transcranial direct current stimulation (tDCS) to modulate lower limb motor network in healthy humans
(2018-08-31)The purpose of this work was to investigate the impact of tDCS applied over the lower limb motor network on cortical excitability, motor learning, and corporal balance control in healthy humans. According to the literature, ... -
Optogenetic characterization of targeting-optimized Chronos and f-Chrimson variants for auditory encoding in mice
(2024-12-03)Electrical cochlear implants bypass the physiological micromechanics and synaptic sound encoding by sensory hair cells in the cochlea and provide state-of-the-art treatment of sensorineural hearing loss. To overcome the ... -
Die Organisation von Signalnetzwerken in B-Lymphozyten
(2012-07-17)B cell antigen receptors (BCR) transduce signals that regulate not only proliferation and differentiation processes but also apoptosis. To regulate such a variety of biological responses BCR employ complex and tightly ... -
Organisation, Expression und Funktion des humanen Peroxisomal-Testis-Specific-1(PXT1)-Gens
(2013-05-29)In this work, organization, expression and function of the human Peroxisomal Testis-specific 1 (PXT1) gene were investigated. The mRNA of the human PXT1 gene doesn’t contain two exons as known so far, but five exons. The ... -
Osteochondrale Transplantation am Kniegelenk – Schicksal der Entnahmedefekte nach Implantation von TruFit®-Zylindern bei großen Knorpeldefekten
(2013-06-18)Because of the potential donor site morbidity cartilage lesions of more than 3 cm² in size are considered to be critical regarding autologous osteochondral transplantation (OCT). In this study the potential donor site ... -
Osteogene und angiogene in vivo Differenzierung auf mit MSC und HUVEC prävaskularisierten Hydroxylapatitmatrizes
(2024-10-11)Autologous transplantation of bone tissue is the gold standard for treating bone defects. Since the complications and limitations of autologous transplantation are diverse, the development of alternatives is of great ... -
Osteoporose - Das Metabolische Syndrom des Knochens - Wirkungen von Ecdyson und Vitamin D auf den postmenopausalen, osteoporotischen Knochen im Zusammenhang mit dem Metabolischen Syndrom
(2014-06-10)Osteoporosis is a systemic skeletal disease, a disease that affects women, especially in the postmenopausal phase of life. At the same time postmenopausal women have an increased risk of getting the metabolic syndrome. ... -
Osteoporose bei Mastozytose
(2017-08-02)Mastocytosis as a cause of secondary osteoporosis is frequently underestimated. Osteoporosis is associated with an increased risk for fractures, which increases morbidity and mortality. It is a retrospective study consisting ... -
Osteoporose bei Mastozytose: Retrospektive Analyse von Betroffenen kutaner oder systemischer Form
(2024-12-09)Mastocytosis is an infiltration of clonal mast cells either in the skin (cutaneous mastocytosis; CM) or at least one extracutaneous organ (systemic mastocytosis; SM). The most frequent systemic subtype is the indolent ... -
Osteoporose bei systemischer Mastozytose: Eine Kohortenstude mit 43 Patienten
(2022-11-16)Introduction
Mastocytosis is a group of rare diseases with a clonal proliferation of mast cells in one or more organs. Systemic mastocytosis has been described as the second most frequent cause of secondary osteoporosis ... -
Outcome und Adhärenz moderierende Faktoren einer intensiven Sportintervention in drei psychiatrischen Störungsentitäten: subjektiver Gesundheitszustand, somatoforme Symptomlast, sportliche Vorerfahrung
(2025-02-06)According to the Global Burden of Disease Study 2010, mental illnesses account for 7.4% of the globally lost healthy life years (Whiteford et al. 2015). Identifying and researching effective therapeutic approaches is ... -
Outcome und Risikofaktoren der Versorgung von distalen Femurfrakturen
(2024-08-19)In the retrospective study, 70 patients with a total of 75 distal femur fractures were examined, who presented as acute patients at the University Medical Center Göttingen from January 2012 to December 2018. The aim of the ... -
Oxaliplatin in der perioperativen, multimodalen Behandlung (präoperative Chemoradiotherapie, TME-Chirurgie und postoperative Chemotherapie) des Rektumkarzinoms – eine monozentrische Analyse –
(2021-02-10)Due to conflicting study results, the use of oxaliplatin (OX) in perioperative multimodal treatment (MMT) for locally advanced adenocarcinoma of the rectum (LARC; clinically staged as cUICC stages II or III) is not recommended ... -
Oxidative stress in the pathogenesis of renal injury: the effect of the antioxidant danshensu on renal fibrosis
(2022-11-29)Chronic kidney disease (CKD), often manifested in its end-stage as renal fibrosis, is a widespread illness, for example in children following congenital urinary obstruction and in adults due to an increasing number of ... -
Oxidativer Stress als Biomarker für die (Neben-) Wirkungen von Strahlentherapie: Bestimmung von Isoprostanspiegeln und Genexpressionsprofilen in Patientenproben
(2011-11-14)Radiotherapy is used to treat prostate cancer as well as locally advanced rectal cancer within a preoperative chemoradiotherapy. To understand the causal relationship between the effect of ... -
Oxidativer Stress und mitochondriale Dysfunktion in einem Mausmodell des Rett-Syndroms.
(2016-07-14)Rett syndrome is a postnatal neurodevelopmental disorder whose major cause are mutations in the methyl-CpG-binding protein 2 (MECP2) gene. It primarily affects girls and it is associated with cognitive impairment, motor ...