Browsing Human- und Zahnmedizin by Title
Now showing items 254-273 of 3378
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Auswirkungen von Dimerisierung auf die Signalgebung der Serotonin-Rezeptoren 2A, 2B und 2C
(2021-11-09)Dimerization of G-protein coupled receptors (GPCRs) has become a big field of research as there is increasing evidence that it has a huge impact on the signaling of receptors. In this work we focused on the group of ... -
Die Auswirkungen von Nikotin und eines Nikotinentzugs auf polysomnografische und neuroendokrine Parameter
(2013-05-10)Nicotine and its withdrawal influence objective markers of sleep and neuroendocrine parameters. This systematic review compares current studies, investigating the effects of nicotine and its withdrawal on sleep, measured ... -
Die Auswirkungen von Ostarine und Raloxifen auf die Skelettmuskulatur im ovarektomierten Rattenmodell
(2024-11-18)Due to demographic change, age-related diseases such as sarcopenia and osteoporosis are becoming an increasing challenge in Germany. One of the main causes of sarcopenia and muscle weakness is low sex hormone concentrations ... -
Auswirkungen von Östradiol, Bisphenol A und Octylmethoxycinnamat in östrogen-sensitiven Organen im Langzeitversuch an ovarektomierten Mäusen
(2012-07-04)Introduction: Today our food, drinks etc. are often in contact with chemicals used in the fabrication for packing. More and more consumers are concerned whether these chemicals lead to an accumulation in the organism ... -
Die Auswirkungen von Tenalisib und Ruxolitinib auf Hodgkin-Lymphom-Zellen und Makrophagen sowie auf deren Interaktion
(2024-09-24)Recent research on Hodgkin lymphoma has shown that the tumor microenvironment, particularly macrophages, plays a role in the development and progression of lymphomas. The underlying mechanisms and the potential therapeutic ... -
Die Auswirkungen von ß-Ecdyson auf die Histomorphologie des Myokards der orchiektomierten Sprague-Dawley-Ratte als Modell des androgendefizienten älteren Mannes
(2014-02-21)20-Hydroxyecdysone (Ecd) has numerous favorable effects on a variety of organs and tissues. It has protective effects on hormone-deficiency associated sarcopenia und osteoporosis. It is devoid of estrogenic and androgenic ... -
Autismus in Niedersachsen
(2025-08-29)Autism is one of the most common neurodevelopmental disorders worldwide. Its prevalence is currently estimated at 1%. In Lower Saxony, this equates to approximately 81,000 people affected. People with autism have a lower ... -
Automated Capillary Electrophoresis Immunoblot for the Detection of Alpha-Synuclein in Mouse Tissue
(2025-08-07)Background: Alpha-synuclein (aSyn) is a key player in neurodegenerative diseases such as Parkinson’s disease (PD), dementia with Lewy bodies, or multiple system atrophy. aSyn is expressed throughout the brain, and can also ... -
Automated Metadata Transformation in a Medical Data Integration Center: Implementation of an Algorithm and Standardized Quality Analysis
(2023-11-02)Evidence-based medicine is the conscientious, explicit, and judicious use of the current best scientific evidence to make informed decisions about the medical care of individual patients. The practice of evidence-based ... -
Automatisierte Thrombuserkennung anhand dünnschichtig rekonstruierter CCT-Schnittbilder
(2023-06-26)In Germany, around 250,000 people suffer a stroke every year. Depending on its severity and extent, a stroke leads to tissue damage and neurological deficits. To evaluate a therapeutic option in the form of intravascular ... -
Autonomie zwischen Ideal und Realität
(2017-07-25)The ethical principle of respect for patient autonomy is widely recognized in contemporary medical science. This undeniably positive development raises a number of questions. The answer to these questions determines whether ... -
Autopsiestudie zur myopathologischen Manifestation klinischer Muskelbeschwerden beim Morbus Parkinson
(2022-08-11)The paraspinal muscles of patients suffering from camptocormia show a recurring pattern of myopathic alterations. Main and secondary criteria for histopathological diagnosis of camptocormia have been defined by Wrede et ... -
Außermedizinische Wünsche am Lebensende von schwer erkrankten Menschen
(2024-01-08)The topic of wishes at the end of life is widely discussed in the media, but mostly limited to aspects of medical treatment at the end of life (e. g. living wills, organ donor cards). For palliative care, the holistic view ... -
Axiographische Darstellung möglicher Unterschiede in der Bewegungsbahn bei okklusions- und kalottenschienengeführter Kondylenbewegung
(2014-09-10)INTRODUCTION: With its various pathologies and etiologies, temporomandibular joint dysfunction is one of the most common disorders of the orofacial system. The many individual symptoms, which often have a marked influence ... -
Axonal transport of autophagosomes in models of neurodegeneration in vitro and in vivo
(2023-12-14)Axonal degeneration is a prevalent hallmark of normal aging, trauma, and neurodegenerative CNS diseases. As an early event, it usually occurs prior to neuronal cell death, which has potential therapeutic implications. ... -
Die axonale Schädigung bei der Multiplen Sklerose: Korrelation von Neurofilament Leichtketten mit histologischen Markern der Axonschädigung und der Klinik
(2023-04-18)Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease associated with axonal injury, and neurofilament light chains in serum (sNfL) are considered a biomarker for this damage. We aimed to investigate the ... -
Axonale Schädigung und Makrophageninfiltration bei Entmarkungserkrankungen
(2025-07-14)Even though the etiology of multiple sclerosis (MS) has been of scientific interest for a long time, it still remains unclear what exactly causes the axonal damage leading to neurological dysfunction. Especially since ... -
Axonpathologie in Immunsubtypen von Multiple-Sklerose-Läsionen
(2013-10-30)Multiple sclerosis (ms) is an inflammatory demyelinating disease of the central nervous system leading to axonal damage. The axonal damage correlates with the degree of clinical disabillity in ms patients. Lucchinetti et ... -
Ärztlich assistierter Suizid – Ein Widerspruch zum ärztlichen Ethos?
(2015-09-18)Medically assisted suicide is a topic in Germany that is currently discussed in a controversial manner. In fact, it especially is a challenge for the medical profession. Since many aspects of physician-assisted suicides ... -
Ärztliche Compliance hinsichtlich Empfehlungen des Giftinformationszentrums-Nord
(2016-08-05)With the establishment of poison control centers in the second half of the twentieth century doctors were the first time adviced based on an evidence-based clinical Toxicologie. In parallel with other medical societies ...