Browsing Human- und Zahnmedizin by Title
Now showing items 670-689 of 3378
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Der Effekt von Phyto- und Sexualhormonen auf den osteoporotischen Knochen der männlichen Rattentibia
(2011-04-12)This study was designed to evaluate the impact of sexualhormons like Dihydrotestosterone (DHT) and oestrogens (E2) versus phytohormones like Genistein (GEN) and Equol (EQU) on orchiectomy-induced ... -
Der Effekt von Strontiumranelat auf lumbale Wirbelkörper osteopenischer Ratten
(2021-06-21)Osteoporosis is a systemic bone disease that affects 200 million people worldwide, predominantly postmenopausal women. Adecreased estrogen level causes a dysbalance between bone formation and bone resorption towards the ... -
Effekte von Angiopoetin-2 auf endotheliale Vorläuferzellen beim akuten ischämischen Nierenversagen der Maus
(2014-05-23)The purpose of this study was to evaluate, whether Angiopoetin-2 (Ang-2) can increase the nephroprotective potential of early endothelial outgrowth cells (eEOCs) in acute murine ischemic kidney injury (AKI). Previously ... -
Effekte chemisch induzierter β-Arrestin-1-Translokation an die Chemokinrezeptoren CXCR4 und CCR5
(2021-07-19)Based on heterodimerization of chemokine receptors CXCR4 and CCR5 with β-arrestin 1 in co-expressing HEK 293 cells, this study shows β-arrestin 1-dependent effects without usual ligand induced receptor and G protein ... -
Effekte der Antiepileptika Carbamazepin und Lamotrigin auf das Prostatakarzinom
(2010-09-01)Several genes are identified which lose or gain their function through cancerogenesis of prostate cancer. Anti epileptic drugs exert their positive effects on prostate cancer cells throughout ... -
Effekte der Barorezeptoraktivierungstherapie auf das Dipping-Verhalten bei Patienten mit therapieresistenter Hypertonie - Eine prospektive Studie mit Non-Dipper-Patienten
(2022-01-25)Non-dipping is defined as an inadequate night-time blood pressure reduction of less than < 10 %. This inadequate reduction as well as an increase in nocturnal blood pressure is associated with an increased cardiovascular ... -
Effekte der Barorezeptoraktivierungstherapie auf Marker des Endoplasmatischen Retikulum Stresses
(2019-11-04)Introduction: Arterial hypertension is present in 30-45% of the adult population and represents a significant public health problem. Although hypertension is one of the major risk factors for the high rate of cardiovascular ... -
Die Effekte der Ca2+-Calmodulin-abhängigen Proteinkinase II (CaMKII) auf die Aktionspotential-morphologie bei mechanischer Last
(2013-10-25)The Calcium2+/Calmodulin-dependent protein kinase II (CaMKII) is a multifunctional serine/threonine protein kinase and acts as a key regulator of excitation contraction coupling in cardiac myocytes. There are several ... -
Effekte der iNOS-Inhibition im transgenen Mausmodell der Einschlusskörpermyositis
(2023-11-01)Background: For Inclusion body myositis (IBM), the most frequent inflammatory myopathy beyond the age of 50, no effective treatment is available. In IBM-muscle an augmented production of nitric oxide (NO) has been identified ... -
Effekte der präsymptomatischen Applikation der Rho-Kinase-Inhibitoren Fasudil und Y-27632 im SOD1-(G93A)-Mausmodell der Amyotrophen Lateralsklerose
(2017-02-20)This study demonstrates the successful pre-clinical testing of a new pharmacological approach in the treatment of amyotrophic lateral sclerosis using Rho-kinase-(ROCK)-inhibition. The Rho/ROCK signal cascade represents an ... -
Effekte der Therapie mit Somatostatin-Analoga bei neuroendokrinen Tumoren
(2016-07-12)In the following retrospective analysis we analyzed data of 66 patients which suffered from NET and were treated in the Universitätsmedizin Göttingen to get to know more about the effects of the therapy with SAA. This Data ... -
Effekte der transkutanen Vagusnervstimulation auf kardiovaskuläre und autonome Parameter
(2024-02-05)Background: Different diseases, including cardiovascular and inflammatory diseases, are associated with a shift in sympathovagal balance in the sympathetic direction. Invasive vagus nerve stimulation is a treatment method ... -
Die Effekte des ERα -Agonisten ZK 281471, dem ERß-Agonisten ZK 281738 auf das Mammagewebe der Sprague-Dawley-Ratte
(2010-06-15)Objective: To describe the interaction between hormone replacement therapy and breast cancer in a histological animal study. Methods: In a period of 30 days, effects of daily ... -
Die Effekte des Wlds-Gens und der Gabe von Nikotinamid auf akute und chronisch-sekundäre Axon-Degeneration
(2021-07-21)Charcot-Marie-Tooth disease (CMT) is the most common inherited neuropathy and a duplication of the peripheral myelin protein of 22 kDa (PMP22) gene causes the most frequent subform CMT1A. Clinical impairments are determined ... -
Effekte einer chronischen β-Adrenozeptor-Blockade auf die Aktivität der Calcium-Calmodulin-Kinase II in der Herzinsuffizienz
(2018-01-22)Heart failure is one of the leading causes of mortality worldwide. Despite major advances in the understanding of heart failure pathophysiology and significant progress in the development of therapeutic concepts, the ... -
Effekte einer pharmakologischen Inhibition der ULK1-Kinase auf die akute axonalen Degeneration in vivo
(2022-09-05)Background: Axonal degeneration is a key and early pathological feature in neurodegenerative and traumatic disorders of the central nervous system. A focal lesion to an axon is followed by a rapid disintegration within ... -
Effekte eines körperlichen Trainingsprogrammes auf die diastolische Funktion und die Leistungsfähigkeit bei Patienten mit diastolischer Herzinsuffizienz
(2012-11-07)This dissertation sought to determine whether structured exercise training improves exercise capacity and diastolic function in patients with heart failure with preserved ejection fraction. A total of 64 patients were ... -
Effekte von Calcitriol auf die renale Fibrogenese
(2012-05-11)Calcitriol may decrease extracellular matrix accumulation in animal models of progressive kidney disease. The mechanisms are only partially understood. In order to understand the antifibrotic effects of calcitriol, we ... -
Effekte von Cisplatin und Carboplatin auf verschiedene Biomarker im Urin
(2016-07-28)Cis- and Carboplatin are frequently part of a cytostatic therapy and have potential nephrotoxic side effects. Early detection of renal damage is of outmost clinical relevance to prevent acute renal failure. However, the ... -
Die Effekte von endokrinen Disruptoren auf den Herzmuskel orchidektomierter Ratten
(2014-04-28)OBJECTIVE The effects of endocrine disruptors (ED) on the reproductive organs are extensively studied as a variety of endocrine disrupting substances have estrogenic and anti-androgenic effects. Since both, estrogen and ...