Closed Publications
Now showing items 1-9 of 9
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Interaktion zwischen ATG2, ATG9 und WIPI4 und ihre Rolle in der Autophagosommebranbildung
(2025-01-21)Autophagy is a cellular recycling mechanism involved in various physiological functions, such as homeostasis, cellular stress response, and nutrient deprivation. A key step in autophagy is the formation of the autophagosome ... -
Die subakuten Effekte des Psilocybin auf Persönlichkeit, Achtsamkeit und die Auflösung des Selbst
(2024-12-10)Psychedelics are a class of drugs that can occasion similar changes in conscious ex- periences mediated via the G-protein coupled Serotonin 2A receptor. These changes vary from slight distortions in perceptions to ... -
Evaluation der Standard Operating Procedure für das Leitsymptom „Abdominelle Schmerzen” in der Klinischen Akut- und Notfallmedizin
(2024-10-11)The leading symptom ‘abdominal pain’ is one of the most common reasons for patient presentation in German emergency departments. It is not only gaining in importance due to its heterogeneity of differential diagnoses and ... -
Rolle des G-Protein-gekoppelten Östrogenrezeptors 1 (GPER1) beim Zervixkarzinom
(2024-03-21)Cervical cancer is the fourth most common cancer in women and after the mamma carcinoma the second most common gynecological carcinoma. The G-Protein-coupled Estrogen Receptor 1 (GPER1) is an important ubiquitous receptor ... -
Die Auswirkungen selektiver ERβ-Agonisten auf ERα-positive Brustkrebszellen hängen von den Expressionsniveaus der Östrogenrezeptoren ERα, ERβ und GPER1 und deren Regulation und Interaktion ab
(2023-12-04)Luminal A breast cancers represent the majority of all breast cancers and are more likely to recur and metastasise. In addition, resistance to tamoxifen is a major treatment problem and new therapeutic options are needed. ... -
Etablierung eines automatisierten Verfahrens zur Quantifizierung von Plasmakonzentrationen direkter oraler Antikoagulantien
(2023-10-12)More than a decade after their first approval, the imageability of direct oral anticoagulants (DOACs) still poses challenges to laboratories worldwide. Even though calibrator- and matrix-dependent chromogenic tests are now ... -
SUMOylierung in Nervenzellen und deren Regulation durch Sauerstoff und Glukose
(2023-04-27)Small ubiquitin-like modifiers (SUMO) are post-translational modifications (PTM) which, similar to Ubiquitin, are conjugated to specific target proteins. The conjugation is based on an energy-dependent enzymatic cascade, ... -
Zusammenhang der Biomarker NT-proBNP und Galectin-3 mit dem psychischen Befinden und der Lebensqualität von Patient*innen mit Herzinsuffizienz und erhaltener Ejektionsfraktion
(2023-04-17)Chronic heart failure is a complex clinical syndrome associated with high mortality, frequent hospitalizations, poor quality of life, and cost-intensive medical care. Based on ejection fraction, the clinical picture is ... -
Einfluss von GnRH Analoga auf die GLUT1 Expression in Ovarialkarzinomzellen und Rolle des GLUT1 Transporters im Tumorwachstum
(2021-08-26)Ovarian cancer is the leading cause of death in women diagnosed with gynecological cancers. Most of the cases are diagnosed at an advanced stage, which leads to poor outcomes of this disease. Chemotherapy makes the women ...