Browsing Human- und Zahnmedizin by Advisor & Referee "Kaulfuß, Silke PD Dr."
Now showing items 1-6 of 6
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Teratome des Hodens mit somatischer Malignität – Eine morphologische, immunhistochemische und molekularpathologische Analyse
(2024-11-11)The prognosis of testicular germ cell tumors, the most common neoplasm in young men, deteriorates when resistance to platinum-based chemotherapy develops. A potential mechanism for this resistance is the development of a ... -
Spermatozytäre Tumoren – Eine Optimierung des diagnostischen Prozesses
(2024-10-11)Spermatocytic tumors are among the gonadal germ cell tumors, which in turn make up the largest proportion of testicular tumors. Spermatocytic tumors are known as tumors of the older man. However, around 30% of patients are ... -
Beeinflusst der knockdown des membranständigen Östrogenrezeptors GPER (GPR30) die anti-invasive Wirksamkeit selektiver Östrogenrezeptor beta (ERb)-Agonisten?
(2023-03-13)The aim of the present work was to investigate to what extent suppression of GPER1 affects viability and invasiveness of TNBC cells. In addition, it was of interest to determine whether suppression of GPER1 affects the ... -
CYR61 und S100A4 als Targets für die Therapie des triple-negativen Mammakarzinoms sowie des Tamoxifen-resistenten Mammakarzinoms
(2022-04-26)Triple-negative breast cancer (TNBC) offers only few therapeutic options due to the lack of ERα and progesterone receptors as well as a non-existing overexpression of HER2. However, even in the case of ERα-positive breast ... -
Der Nachweis eines Isochromosoms i[12p] in malignen Keimzelltumoren mittels qPCR
(2021-09-28)The germ cell tumour is the most common malignant neoplasm in young men. The majority are germ cell tumours type II, which are divided into seminomas and non-seminomas. What these tumours have in common is that there is a ... -
Genetische Suszeptibiliätstestung für sporadische Alzheimer-Demenz: Analyse medizinethischer Probleme im Spannungsfeld von Autonomie und Verantwortung
(2018-06-20)Alzheimer’s disease (AD) is the most common cause of dementia and a major public health concern. Currently, neither prevention nor treatment exists to cure or stop the fatal disease. Findings suggest that neurodegeneration ...