Browsing Human- und Zahnmedizin by Advisor "Mihm, Sabine Prof. Dr."
Now showing items 1-6 of 6
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Assoziation des PDCD1 rs11568821 GG-Genotyps mit stärkerer Morbidität bei Intensivpatienten mit Krankheitsbild Sepsis: Vergleich der SOFA-Sub-Scores
(2016-06-20)The failing of various therapeutic agents in the treatment of sepsis elucidates the still existing lack of knowledge of this syndrome. Over the last years a major change has taken place as results have shown that, beside ... -
Genetische Polymorphismen in Typ-III-Interferon-Genen und deren prognostische Signifikanz für das hepatozelluläre Karzinom und das duktale Pankreasadenokarzinom
(2021-03-08)Hepatocellular carcinoma (HCC) and pancreatic ductal adenocarcinoma (PDAC) are malignancies with a leading lethality. With reference to interferons (IFNs) known to mediate antitumor activities, this study investigated the ... -
The Effects of Conventional Chemotherapeutics on the Activation of Type I Interferons (IFN-α/β) in Hepatic Cancer Cells in vitro: The Significance of Endogenous Type III Interferons (IFN-λ)
(2023-04-24)HCC is characterized by limited therapy options, poor response rates to systemic chemotherapy, and high lethality. Preclinical cancer models have revealed the efficacy of genotoxic drugs to rely on the release of type I ... -
Therapiestrategien bei Patienten mit Hepatitis-C-Virusinfektion an der Universitätsmedizin Göttingen: Eine retrospektive Analyse von Therapieergebnissen
(2016-06-07)Worldwide 80-160 million people are estimated to be chronically infected with the hepatitis C virus (HCV), a single stranded RNA virus. Chronic HCV infection is a leading cause of liver specific morbidity and mortality ... -
Untersuchungen zur Assoziation genetischer Polymorphismen im Gen des Endotoxinrezeptors CD14 mit der transkriptionellen Aktivität
(2011-01-20)Association of the polymorphism rs2569190 within the CD14 endotoxin receptor gene with various disease conditions containing an inflammatory component and further in vitro experiments with ... -
Zytokinabhängige Expression von EGF und VEGF und ihrer Rezeptoren EGFR und VEGFR-1 im Tumormikromilieu des kolorektalen Karzinoms
(2014-06-23)Several diseases associated with chronic inflammation - for example gastro-esophageal reflux, Helicobacter pylori infection and chronic (gastro)enteritis in the context of inflammatory bowel disease (IBD) - promote tumor ...