Browsing Human- und Zahnmedizin by Advisor "Wilting, Jörg Prof. Dr."
Now showing items 1-11 of 11
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Untersuchung spezifischer Inhibitoren der PI3K-Signalkaskade zur Therapie des Lymphangioms
(2020-07-06)Lymphatic malformations (LM; lymphangiomas) are benign congenital malformation disorders of the lymphatic system and are characterized by cystic lymphatic enlargements. A distinction is made between the macrocystic, ... -
Morphologische Charakterisierung von Wnt5a Knock-out-Mäusen: Eine licht- und elektronenmikroskopische Untersuchung des dermalen Lymphgefäßsystems
(2019-05-27)Lymphatic vessels are essential for the maintenance of tissue homeostasis. Their primary functions are the return of excessive tissue fluid into blood circulation, the transport of antigens both in soluble form and after ... -
Effekt ionisierender Strahlung auf das Blut- und Lymphgefäßsystem der Chorioallantoismembran des Hühnerembryos
(2019-03-12)In this thesis, the effect of ionizing radiation on the vessels of the chorioallantoic membrane (CAM) of the chick embryo is evaluated. Both, the lymphatic and the blood vessels were studied in the CAM in vivo model. After ... -
Proliferationsuntersuchungen zur Entwicklung des Lymphgefäßsystems bei Wnt5a-transgenen Mäusen
(2018-04-27)Wnt5a is a secreted glycoprotein and represents one of the 19 members of the human WNT-gene-family, which regulate embryonic development. In contrast to most other members of the Wnt-family, Wnt5a also is a regulator of ... -
Ultrastructural characterization of human thigh lymphatic collectors
(2018-01-04)Lymphedema is a condition that affects millions of patients worldwide. Most of the research has been performed on animals, while the cellular and molecular characteristics of human lymphatic collectors have been largely ... -
Die Bedeutung von Reelin beim Neuroblastom
(2013-07-05)Neurblastoma is a malignant tumor of early childhood. Its heterogeneity is reflected in its biological properties as well as clinical outcome. In this theses work, I have investigated the function of reelin, an extracellular ... -
Charakterisierung von Ratten-Myofibroblasten des Gastrointestinaltrakts und der Leber unter Berücksichtigung mikroskopischer und molekularbiologischer Aspekte
(2013-04-30)Myofibroblasts (MF) are connective tissue cells with properties of smooth muscle cells and fibroblasts. In contrast to normal fibroblasts they express alpha smooth muscle actin (α-SMA) and Thy-1. MF have influence on the ... -
Immunhistologische Untersuchungen venöser Malformationen
(2011-08-05)Venous malformations (VMs) are the largest group of vascular malformations of neonates representing more than 50 % of cases. In a large group of spontaneous mutations of VMs the primary ... -
Der Transkriptionsfaktor Hex markiert eine Subpopulation von Endothelzellen bei der Embryonalentwicklung und der Tumorangiogenese
(2011-02-15)The homeobox gene Hex regulates numerous development processes in vertebrates and controls the cell proliferation and differentiation within this. Main purpose of this study is to examine ... -
Die Bedeutung von Monocyte Chemotactic Protein - 1 (MCP - 1) für die Angiogenese des Glioms
(2010-10-29)Gliomas are well vascularized tumors. Turmorangiogenese is strongly affected by angiogenesis factors. This shows a pronounced angio- and Venogenesis of experimental MCP-1 producing CNS-1 ... -
Immunhistologische Charakterisierung experimenteller Lymphangiome der Maus
(2009-12-04)A mouse lymphangioma model has been established by injecting Freund's incomplete adjuvant (FIA) intraperitoneally. We show that, in accordance with studies from the 1960s, the mouse model ...