Browsing Human- und Zahnmedizin by Advisor "Wolff, Hendrik PD Dr."
Now showing items 1-8 of 8
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Radio(chemo)therapie des Zervixkarzinoms – Klinische Ergebnisse mit intensitätsmodulierter Rotationsbestrahlung und konventioneller 3D-Bestrahlung im Vergleich
(2020-08-24)Abstract Purpose Intensity-modulated radiotherapy (IMRT) for cervical cancer yields favorable results in terms of oncological outcomes, acute toxicity, and late toxicity. Limited data are available on clinical results ... -
Analyse der Expression von Chemokinen und Chemokinrezeptoren in Kopf-Hals-Tumorzellen
(2018-03-08)Radiotherapy plays an important role in the treatment of malignant head and neck tumors. Chemokines are chemotactic cytokines, which can induce tumor proliferation as well as metastasis, although the influence of chemokines ... -
Experimentelle Untersuchungen zur Strahlenempfindlichkeit von Lymphozyten bei Patienten mit lokal fortgeschrittenem Rektumkarzinom
(2017-03-08)A neoadjuvant radio –and chemotherapie as standard of the multimodal treatment of the locally advanced rectal cancer causes damages of the DNA that can be detected in peripheral blood lymphocytes (PBL). After acquisition ... -
Einfluss von Keimbahn-Polymorphismen in Genen des TGFβ-Signalwegs und der DNA-Reparatur auf die Strahlenempfindlichkeit Humaner Lymphoblastoider Zellen
(2017-02-24)Besides chemotherapeutic and surgical treatments radiotherapy is an integral element of multimodal therapeutic concepts in malign tumor diseases. In this context the insight in physiological and pathophysiological processes ... -
Analyse der Expression von Chemokinen und Chemokinrezeptoren in HNO-Tumorzellen unter Radiochemotherapie
(2017-02-20)As patients suffering from squamous cell carcinoma of the head and neck (SCCHN) commonly have a poor prognosis, there is a need to understand the impacts on the behaviour of tumor cells better. It is already known that ... -
Einflussnahme von TGFβ auf die Strahlensensibilität lymphoblastoider Zellen
(2016-04-11)In this thesis 48 commercially purchased lymphoblastoid cell lines (LCLs) were used to investigate the effects of 1771 gene polymorphisms out of 23 candidate genes on genomic damages following various treatments. Therefore ... -
Auswirkungen einer Radiochemotherapie auf die Zytokinkonzentration im Plasma von Patienten mit einem Plattenepithelkarzinom im Kopf-Hals-Bereich
(2015-06-29)Background: The prognosis of patients having a SCCHN is still poor despite of several different therapies that have been established. Aim: The purpose of this work was to analyze the concentrations of the chemokines CCL2, ... -
Experimental study of the combined effect of irradiation, lovastatin, and monoclonal antibodies on tumour and normal tissue cell lines. Its genesis and mechanisms of action
(2014-09-30)Statins, as lipid-lowering agents, were described to possess an anti-cancer potential. For this reason, in vitro effect of combined treatment by lovastatin and irradiation was explored in order to find a radiosensitizing ...