Dokumente Human- und Zahnmedizin nach Gutachter "Hardeland, Rüdiger Prof. Dr."
Anzeige 1-8 von 8
-
Regulation by Glycogen Synthase Kinase-3 Beta of CBP transcriptional coactivator involved in insulin-dependent glucagon gene transcription
(2007-02-12)The peptide hormone glucagon is a functional antagonist of insulin and it stimulates glucose output from the liver. Insulin inhibits glucagon secretion and glucagon gene transcription. ... -
Regulation of gene expression of hepcidin and of other proteins of the iron metabolism in the liver and in the extrahepatic tissues: in vivo and in vitro studies in different rat models.
(2006-12-04)Iron is an essential element required for many redox processes in all eukaryotes and most of the prokaryotes. Serum iron level decreases during microbial infection, inflammation or ... -
Molecular mechanisms of insulin resistance in glucagon-producing alpha cells
(2006-11-22)Type II diabetes mellitus is a chronic disease, affecting more than 150 million people worldwide. Type II diabetes mellitus is characterized by insulin resistance of peripheral tissues ... -
Transcriptional regulation of the Human Zfm1/Sf1 Gene
(2006-10-12)The first aim of the present study was to elucidate whether IL-1β/TNFα and/or PDGF down-regulate Zfm1 gene expression and induce proliferation also in human SMC. The results revealed that ... -
Expression und Wirkungsmechanismen von Gonadotropin-Releasing Hormon Typ II (GnRH-II) und seines Rezeptors in humanen Ovarial- und Endometriumkarzinomen
(2006-07-13)The majority of human endometrial- (>80%) and ovarian (>80%) cancer cell lines express gonadotropin releasing hormone (GnRH-I) and its receptor as a part of a negative autocrine/paracrine ... -
Untersuchung der Differenzierungskapazität von Osteoblasten und Osteoblastensubpopulationen in vitro und ihre Beeinflussung durch verschiedene Wuchsfaktoren
(2005-09-02)Knowledge of the basic mechanisms controlling osteogenesis and adipogenesis might provide new insights into the prevention of osteoporosis and age-related osteopenia. In this study, ... -
Characterization of ENTH domain proteins and their interaction with SNAREs in S.cerevisiae
(2005-07-29)SNAREs play an important role in the membrane fusion events as fusogenic proteins. Therefore, localization and activity of SNAREs has to be tightly controlled. Regulatory proteins ... -
De novo Induktion von Anaphylatoxin C5a-Rezeptoren in Hepatocyten der Ratte durch den Entzündungsauslöser Lipopolysaccharid in vivo
(2002-08-01)In normal rat liver, anaphylatoxin C5a receptors (C5aR) are only expressed by nonparenchymal cells, mainly Kupffer cells and hepatic stellate cells, weakly by sinusoidal endothelial ...