Browsing Human- und Zahnmedizin by Referee "Johnsen, Steven Prof. Dr."
Now showing items 1-6 of 6
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Anreicherung und semiautomatisierte Detektion HER2-positiver zirkulierender Tumorzellen im Mammakarzinom
(2023-03-09)In clinical practice HER2 status has so far been determined using tissue samples from biopsies. As sample collection is an invasive, time-consuming procedure for patients, the focus is nowadays on blood-based biomarkers ... -
Characterization of Interleukin 10 gene variations and serum levels as predictive factors for the clinical outcome of Non-Hodgkin Lymphoma patients and Analysis of molecular mechanisms of Interleukin 10 gene regulation in B cells
(2013-03-06)Aggressive Non-Hodgkin lymphoma (aNHL) comprises a heterogeneous group of lymphatic malignancies. Although current treatment regiments can achieve high response rates, many patients do not achieve complete remission. ... -
Functional Assessment of Biomarkers in Gemcitabine-Treated Pancreatic Cancer with Specific Focus on Nucleoside Transporter ENT1
(2013-10-31)Pancreatic ductal adenocarcinomas are the fourth leading cause of death among all kinds of cancers. The poor prognosis is due to usually late diagnosis and, in most cases, the available therapeutic options lack sustained ... -
Die Funktionsanalyse und Pharmakomodulation des Amyloid-Vorläufer-Proteins (APP) in vitro und in vivo - Eine neue Zielstruktur zur Behandlung maligner Tumore
(2012-02-28)The ß-amyloid precursor protein (APP) represents a type I transmembrane glycoprotein that is ubiquitously expressed in neuronal as well as in non-neuronal cells. In brain it is a key player ... -
Interaktionen von humanen mesenchymalen Stromazellen (hMSC) mit Plattenepithelkarzinomzellen des Oropharynx in indirekter Kokultur
(2011-05-16)Head and neck squamous cell cancer (HNSCC) is the most frequent malignant tumor of the oropharyngeal region. Population-based cancer statistics show only little evidence of improvement in ... -
Die Rolle von ARID1A in Pankreas- und kolorektalem Karzinom
(2023-05-23)Overall, ARID1A showed a strongly context-dependent function in this study (Sun et al. 2017). In particular, in pancreatic tumors, the tumor suppressive function of ARID1A could be partially confirmed in terms of growth ...