Browsing Human- und Zahnmedizin by Referee "Johnsen, Steven A. Prof. Dr."
Now showing items 1-7 of 7
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B Cell Antigen Receptor-intrinsic Costimulation of IgG and IgE Isotypes
(2012-06-27)B cells express different isotypes of the B cell antigen receptor (BCR) on their surface and secrete soluble forms of their antigen binding immunoglobulins (Ig) upon differentiation to plasma cells. Naïve mature B cells ... -
Einfluss von RhoA auf die Invasivität von Mammakarzinomzellen
(2021-05-20)Breast cancer is the most frequent cancer women suffer from. The most common cause of death is metastasis not the tumor itself, in this stage the disease is no longer curable. This underlines the great significance of ... -
Expression und Funktion des Vitamin-D-Rezeptors in malignen Keimzelltumoren des Hodens
(2011-02-25)Testicular germ cell tumours (TGCT) are the most common malignancy in young men. They are clinical and histological subdivided in seminomas and non-seminomas. 1,25-dihydroxyvitamin D3 ... -
Investigation of TRAIL resistance in ovarian cancer cell lines and translational application in primary ovarian cancer cells
(2011-09-21)Ovarian cancer, the deadliest of the gynaecologic malignancies, poses a therapeutic challenge because of the 70% recurrence rate among patients treated with taxane/platinum-based chemotherapy. ... -
Die Rolle des Chromatinmodulators CHD1 im kastrationsresistenten Prostatakarzinom
(2021-09-02)Current therapy of metastasized prostate cancer largely depends on androgen-deprivation therapy (ADT). Despite initial response, tumors inevitably reach castration resistance (CRPC), a stage at which chemotherapy and ... -
Verstärkung der Antitumorwirkung von Estrogenantagonisten durch die Kombination mit einem GnRH-II-Antagonisten, angewandt an Zelllinien des Ovarialkarzinoms
(2016-07-14)Over the last years GnRH-II-antagonists have presented a focus of interest in the endocrine therapy of gynecological and other cancers such as prostate cancer. It was shown that GnRH-II-antagonists even in nanomolar ... -
Die Wirkung von GnRH-Analoga auf die Expression von Wachstumsfaktoren und deren Rezeptoren in humanen Mammakarzinomzellen und der Osteoblasten-ähnlichen Zellreihe MG-63 während der Kokultur
(2016-01-13)Breast cancer is the most common cancer of women worldwide. In the advanced stage of the disease, up to 75% of all patients develop bone metastases. Based on the finding that GnRH analogues inhibit the migration and ...