Browsing Human- und Zahnmedizin by Referee "Lehnart, Stephan E. Prof. Dr."
Now showing items 1-3 of 3
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Development of a Novel Fluorescence Indicator System for the Characterization of Sarcomere Organization an Function in Human Cardiomyocytes
(2022-03-16)In this work, we describe a novel fluorescence indicator system for the in-vitro characterization of human stem cell-derived cardiomyocytes (hPSC-CM). We hypothesized that a) Z-lines in hPSC-CM can be reliably labeled via ... -
Dreifarbige STED-Nanoskopie von Calcium-Freisetzungseinheiten in humanem linksventrikulären Gewebe verschiedener Subtypen hochgradiger Aortenklappenstenose
(2023-07-24)Confocal microscopy and STED nanoscopy of left ventricular myocardial biopsies from patients with severe aortic valve stenosis were used to investigate mechanisms of dysfunctional cardiac remodeling at the cellular and ... -
Einfluss der Herzinsuffizienz auf Membranstrukturen und lokale cAMP-Dynamiken der SERCA2a-Mikrodomäne
(2016-10-17)Despite various therapeutic options, heart failure is still one of the main chronic diseases and causes of death in Western industrial nations. The signaling cascade of 3‘,5’-cyclic adenosine monophosphate (cAMP) plays a ...